ArticleInvestigative ophthalmology & visual science2021
Longitudinal Changes in Macular Optical Coherence Tomography Angiography Metrics in Primary Open-Angle Glaucoma With High Myopia: A Prospective Study.
Article in Investigative ophthalmology & visual science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Intraocular Pressure-Lowering Therapy Slows Down Axial Elongation in Progressive High Myopia with Enhanced Choroidal Perfusion.Ophthalmology science · 2026Article
- Evaluation of OCT Angiography Parameters as Biomarkers for Glaucoma Progression.Diagnostics (Basel, Switzerland) · 2025Article
- Detecting Glaucoma in Highly Myopic Eyes From Fundus Photographs Using Deep Convolutional Neural Networks.Clinical & experimental ophthalmology · 2025Article
- Retinal microvascular changes in patients with pancreatitis and their clinical significance.Scientific reports · 2024Article
- Peripheral Ganglion Cell Complex Thickness and Retinal Microvasculature in Myopia Using Wide-Field Swept-Source OCT.Translational vision science & technology · 2024Article
- Assessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia.Ophthalmology and therapy · 2024Article
- Early changes in photopic negative response in eyes with glaucoma with and without choroidal detachment after filtration surgery.The British journal of ophthalmology · 2023Observational
- Evidence of vascular involvement in myopia: a review.Frontiers in medicine · 2023Review
- Association of macular structure, function, and vessel density with foveal threshold in advanced glaucoma.Scientific reports · 2022Article
- Relationship Between Deep Retinal Macular Vessel Density and Bipolar Cell Function in Glaucomatous Eyes.Translational vision science & technology · 2022Article
- Association of Superficial and Deep Macular Microvasculature with Central Visual Field Sensitivity in Glaucomatous Eyes with High Myopia.Journal of clinical medicine · 2022Article
- Advances in OCT Imaging in Myopia and Pathologic Myopia.Diagnostics (Basel, Switzerland) · 2022Review
- Ocular Factors of Fractal Dimension and Blood Vessel Tortuosity Derived From OCTA in a Healthy Chinese Population.Translational vision science & technology · 2022Article
- The characteristics of fundus microvascular alterations in the course of glaucoma: a narrative review.Annals of translational medicine · 2022Review
- Peripapillary vessel density correlates with visual field mean sensitivity in highly myopic eyes.Journal of translational medicine · 2022Article
- Macular Retinal Microvasculature of Hyperopia, Emmetropia, and Myopia in Children.Frontiers in medicine · 2022Article
- Peripapillary Vascular Reactivity in Primary Open-Angle Glaucoma With High Myopia by Using Optical Coherence Tomography Angiography.Frontiers in medicine · 2022Article
- Longitudinal Macular Retinal and Choroidal Microvasculature Changes in High Myopia.Investigative ophthalmology & visual science · 2021Article
- Retinal Microvasculature and Conjunctival Vessel Alterations in Patients With Systemic Lupus Erythematosus-An Optical Coherence Tomography Angiography Study.Frontiers in medicine · 2021Article
- Study on the Optic Nerve Fiber Layer Thickness and Changes in Blood Flow in Myopic Children.International journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To characterize longitudinal changes in macular microvasculature as quantified from optical coherence tomography angiography (OCTA) metrics in primary open-angle glaucoma (POAG) eyes with and without high myopia. Methods: In total, 63 and 61 POAG eyes with and without high myopia, respectively, underwent swept-source OCTA imaging in at least four follow-up visits at an ophthalmic center, with a scanning protocol of 3- × 3-mm centered at the fovea. The foveal avascular zone (FAZ) area, FAZ circularity, and vessel density (VD) in both the superficial (SCP) and deep capillary plexuses (DCP) were measured. The rate of change in macular OCTA metrics over time was estimated using linear mixed-effects models in both groups of POAG eyes. Results: The mean follow-up time and number of visits were 27.72 ± 8.57 months and 8.5 (8 to 13) times, and 30.95 ± 10.19 months and 10 (8‒13) times in POAG eyes with and without high myopia, respectively. VD in the DCP reduced significantly more quickly in POAG eyes with high myopia than in those without high myopia (-5.14%/year vs. -3.71%/year, P = 0.008). Moreover, lower baseline VD in the DCP was significantly associated with faster VD reduction in POAG with high myopia eyes (P < 0.001). Conversely, the VD reduction rate in the SCP, FAZ area, and FAZ circularity in both the SCP and DCP were similar in both groups (all Ps > 0.05). Conclusions: VD in DCP reduced significantly more quickly in POAG eyes with high myopia over time. Density in the DCP reduced more quickly when baseline VD was low.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.