Evidence mapPaperPMID 33508993Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets.

Dimitrios Tsikas, Stepan Gambaryan

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Dimitrios TsikasInstitute of Toxicology, Core Unit Proteomics, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-6320-0956
Stepan GambaryanSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Petersburg, Russia.ORCID https://orcid.org/0000-0002-1470-0791
Institute of Evolutionary Physiology and Biochemistry · RUMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The carbonic anhydrase (CA) family does not only catalyse the reversible hydration of CO

Indexed as

Blood PlateletsCarbonic Anhydrase IICell Adhesion MoleculesCysteineHumansMicrofilament ProteinsNitric OxideNitrite ReductasesOxidoreductasesPhosphoproteinsPhosphorylationVasodilator-Stimulated PhosphoproteinCarbonic Anhydrase IICell Adhesion MoleculesCysteineMicrofilament ProteinsNitric Oxidenitrite dehydrogenaseNitrite ReductasesOxidoreductasesPhosphoproteinsVasodilator-Stimulated PhosphoproteinCarbonic anhydraseH2 18Omass spectrometrynitrous anhydrase activity

Identifiers

PMID33508993
PMCPMC7875556
OpenAlexW3121708734

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.