Evidence map›Paper›PMID 33509767›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Overexpression of lncRNA MEG3 inhibits proliferation and invasion of glioblastoma U251 cells

Qizhi Luo, Fan Zhang, Wei Li, Fang Wang, Lixiang Wu, Baisheng Huang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qizhi LuoDepartment of Immunology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Fan ZhangDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Wei LiDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Fang WangDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Lixiang WuDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Baisheng HuangDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410008, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of overexpression of long noncoding RNA (lncRNA) MEG3 on the proliferation and invasion of glioblastoma U251 cells by suppressing the expression of hypoxia inducible factor 1

methodsThe expression of lncRNA MEG3 and HIF1

resultsThe expression of MEG3 was significantly lower and HIF1

conclusionsMEG3 overexpression inhibits the proliferation and invasion of U251 cells through suppressing the expression of HIF1

Indexed as

GlioblastomaMicroRNAsRNA, Long NoncodingApoptosisCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansMicroRNAsRNA, Long Noncodingglioblastomahypoxia inducible factor 1 alphainvasionlong noncoding RNA MEG3proliferation

Identifiers

PMID33509767
PMCPMC7867485
OpenAlexW3206045602

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.