Evidence map›Paper›PMID 33510350›Full record

ArticleScientific reports2021

Genome-wide comparative analyses reveal selection signatures underlying adaptation and production in Tibetan and Poll Dorset sheep.

Yingyue Zhang, Xianglan Xue, Yue Liu, Adam Abied, Yangyang Ding, Shengguo Zhao, Wenqiang Wang, Liqing Ma, Jijun Guo, Weijun Guan and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
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  7. Exploring the genetic footprints of high altitude adapted humans and livestock.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
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  19. A novel 22-bp InDel withinAnimal biotechnology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Yingyue Zhang *Institute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Xianglan Xue *Institute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Yue LiuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Adam AbiedInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Yangyang DingInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Shengguo ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, People's Republic of China.
Wenqiang WangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, People's Republic of China.
Liqing MaQinghai Academy of Animal Science and Veterinary Medicine, Xining, 810016, People's Republic of China.
Jijun GuoAnimal Husbandry and Veterinary Service of Qinghai, Xining, 810001, People's Republic of China.
Weijun GuanInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Yabin PuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Joram M MwacharoInternational Centre for Agricultural Research in the Dry Areas (ICARDA), P.O. Box 5689, Addis Ababa, Ethiopia.
Jianlin HanInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China.
Yuehui MaInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China. yuehui.ma@263.net.
Qianjun ZhaoInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, 100193, People's Republic of China. zhaoqianjun@caas.cn.
Institute of Animal Sciences · CNChinese Academy of Agricultural Sciences · CNGansu Agricultural University · CNXinjiang Academy of Animal Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of genome-wide selection signatures can provide insights on the mechanisms of natural and/or artificial selection and uncover genes related to biological functions and/or phenotypes. Tibetan sheep are an important livestock in Tibet, providing meat and wool for Tibetans who are renown for breeding livestock that adapt well to high altitudes. Using whole-genome sequences with an effective sequencing depth of 5×, we investigated the genomic diversity and structure and, identified selection signatures of White Tibetan, Oula and Poll Dorset sheep. We obtained 30,163,679 Single Nucleotide Polymorphisms (SNPs) and 5,388,372 indels benchmarked against the ovine Oar_v4.0 genome assembly. Next, using F

Indexed as

Polymorphism, Single NucleotideAdaptation, PhysiologicalAnimalsGenome-Wide Association StudySheepSpecies Specificity

Identifiers

PMID33510350
PMCPMC7844035
OpenAlexW3124541244

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.