Evidence map›Paper›PMID 33513820›Full record

Trial reportNutrients2021

Safety and Efficacy of Probiotic Supplementation in Reducing the Incidence of Infections and Modulating Inflammation in the Elderly with Feeding Tubes: A Pilot, Double-Blind, Placebo-Controlled Study, "IntegPRO".

Paolo Orlandoni, Nikolina Jukic Peladic, Angela Amoruso, Marco Pane, Mirko Di Rosa, Jennifer Vedruccio, Franco Santini

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Paolo OrlandoniClinical Nutrition Unit, National Institute of Health and Science on Aging, IRCCS INRCA Ancona, Via della Montagnola 81, 60127 Ancona, Italy.
Nikolina Jukic PeladicClinical Nutrition Unit, National Institute of Health and Science on Aging, IRCCS INRCA Ancona, Via della Montagnola 81, 60127 Ancona, Italy.
Angela AmorusoProbiotical Research Srl, Via E.Mattei 3, 28100 Novara, Italy.ORCID 0000-0001-5919-2658
Marco PaneProbiotical Research Srl, Via E.Mattei 3, 28100 Novara, Italy.
Mirko Di RosaUnit of Geriatric Pharmacoepidemiology and Biostatistics, National Institute of Health and Science on Aging, IRCCS INRCA Ancona, Via Santa Margherita 5, 60124 Ancona, Italy.ORCID 0000-0002-1862-4159
Jennifer VedruccioResidenza Conero Santo Stefano, SS 16 Via Flaminia 293 326/A, 60020 Ancona, Italy.
Franco SantiniEx Medical Direction, Errekappa Euroterapici S.p.A., Via Ciro Menotti 1/A, 20129 Milan, Italy.
Istituto Nazionale di Riposo e Cura per Anziani · ITProbiotical (Italy) · ITIstituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A double-blind, placebo-controlled study was performed in a sample of geriatric patients treated with home enteral nutrition (HEN) to analyze the efficacy of a probiotic supplement Proxian

Indexed as

Enteral NutritionAgedAged, 80 and overAnti-Bacterial AgentsBifidobacterium animalisC-Reactive ProteinDefecationDouble-Blind MethodFemaleFollow-Up StudiesHumansIncidenceInflammationLactiplantibacillus plantarumLactobacillusMaleAnti-Bacterial AgentsC-Reactive ProteinSeleniumZincenteral nutritiongeriatric patientsinflammationprobiotics

Identifiers

PMID33513820
PMCPMC7911800
OpenAlexW3121315824

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.