Evidence mapPaperPMID 33514002Full record

SynthesisNutrients2021

Potential Therapeutic Effects of Curcumin on Glycemic and Lipid Profile in Uncomplicated Type 2 Diabetes-A Meta-Analysis of Randomized Controlled Trial.

Emma Altobelli, Paolo Matteo Angeletti, Ciro Marziliano, Marianna Mastrodomenico, Anna Rita Giuliani, Reimondo Petrocelli

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 9 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 9 syntheses or guidelines pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emma AltobelliDepartment of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Paolo Matteo AngelettiDepartment of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Ciro MarzilianoDepartment of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Marianna MastrodomenicoDepartment of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Anna Rita GiulianiDepartment of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Reimondo PetrocelliPublic Health Unit, ASREM, 86100 Campobasso, Italy.
University of L'Aquila · ITConsorzio Milano Ricerche · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is an important issue for public health, and it is growing in the world. In recent years, there has been a growing research interest on efficacy evidence of the curcumin use in the regulation of glycemia and lipidaemia. The molecular structure of curcumins allows to intercept reactive oxygen species (ROI) that are particularly harmful in chronic inflammation and tumorigenesis models. The aim of our study performed a systematic review and meta-analysis to evaluate the effect of curcumin on glycemic and lipid profile in subjects with uncomplicated type 2 diabetes. The papers included in the meta-analysis were sought in the MEDLINE, EMBASE, Scopus, Clinicaltrials.gov, Web of Science, and Cochrane Library databases as of October 2020. The sizes were pooled across studies in order to obtain an overall effect size. A random effects model was used to account for different sources of variation among studies. Cohen's

Indexed as

Blood GlucoseCholesterol, HDLCholesterol, LDLCurcuminDiabetes Mellitus, Type 2Glycated HemoglobinHumansRandomized Controlled Trials as TopicTriglyceridesBlood GlucoseCholesterol, HDLCholesterol, LDLCurcuminGlycated HemoglobinTriglyceridescurcumadyslipidemiameta-analysisrandomized control trialturmerictype 2 diabetes

Identifiers

PMID33514002
PMCPMC7912109
OpenAlexW3122741988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.