Evidence map›Paper›PMID 33514607›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2021

Glutathione

Leilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Ye Zhi-Wei, Zhang Jie, Danyelle M Townsend, Kenneth D Tew

Erratum issuedOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Leilei ZhangLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Seok-Hyung KimLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Ki-Hoon ParkLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Ye Zhi-WeiLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Zhang JieLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Danyelle M TownsendLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina.
Kenneth D TewLeilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew Department of Cell and Molecular Pharmacology and Experimental Therapeutics (L.Z., Z.Y., J.Z., K.D.T.), Division of Nephrology, Department of Medicine (S.-H.K., K.-H.P.), and Department of Pharmaceutical and Biomedical Sciences (D.M.T.), Medical University of South Carolina, Charleston, South Carolina tewk@musc.edu.
Medical University of South Carolina · US

Funding

Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RICHARD R. DRAKE · 2020 to 2026
$8.8M
SOUTH CAROLINA COBRE IN OXIDANTS, REDOX BALANCE AND STRESS SIGNALINGP20RR024485 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI TEW, KENNETH D. · 2011 to 2011
$2.2M
MUSC FACIL EXPANSION &RENOV: SLE C06RR015455 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CROUCH, ROSALIE K · 2002 to 2002
$2.0M
PRECLINICAL DEVELOPMENT OF A GLUTATHIONE BASED CANCER DRUGR41CA117259 · NCI · CELLECTAR BIOSCIENCES, INC. · PI TEW, KENNETH D. · 2007 to 2007
$150k
NCI NIH HHS R41 CA117259NCRR NIH HHS C06 RR015455NCRR NIH HHS P20 RR024485NIDDK NIH HHS P30 DK123704
6 · The paper itself

Abstract

We have created a novel glutathione

Indexed as

Unfolded Protein Response4-Aminobenzoic AcidActivating Transcription Factor 4AnimalsExtracellular Signal-Regulated MAP KinasesGlutathione S-Transferase piHomeostasisLarvaNF-E2-Related Factor 2Nitric OxideOxidantsOxidation-ReductionTranscriptomeTunicamycinZebrafishZebrafish Proteins4-Aminobenzoic AcidActivating Transcription Factor 4Extracellular Signal-Regulated MAP KinasesGlutathione S-Transferase pinfe2l2a protein, zebrafishNF-E2-Related Factor 2Nitric OxideOxidantsTunicamycinZebrafish Proteins

Identifiers

PMID33514607
PMCPMC8047768
OpenAlexW3122262137

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.