Evidence map›Paper›PMID 33518179›Full record

ReviewEndocrinology and metabolism clinics of North America2021

Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

Sydney Chang, Andrea Dunaif

Abstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Association between exposure to endocrine-disrupting chemicals and polycystic ovary syndrome: a systematic review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Visceral adiposity and insulin resistance in polycystic ovarian syndrome - A cross-sectional, observational study.European journal of obstetrics & gynecology and reproductive biology: X · 2026
    Article
  10. Review
  11. MASLD coexisting with PCOS increases cardiometabolic risk.The Journal of clinical endocrinology and metabolism · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sydney ChangDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Zucker School of Medicine at Hofstra/Northwell, 210A E 64th St. 1st Floor, New York, NY 10065, USA.
Andrea DunaifDepartment of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, Atran Building, 1428 Madison Avenue, 4th Floor, Room 4-36, New York, NY 10029, USA. Electronic address: andrea.dunaif@mssm.edu.

Funding

Genetically Validated PCOS Subtypes: Data-Driven Clinical Translation for Improved Diagnosis and Comprehensive Risk StratificationR01HD100812 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Andrea Dunaif · 2020 to 2026
$4.1M
Multiethnic Fine-Mapping of Polycystic Ovary Syndrome Susceptibility LociR01HD085227 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHEN, ZIJIANG, DUNAIF, ANDREA E · 2016 to 2020
$3.2M
NICHD NIH HHS R01 HD085227NICHD NIH HHS R01 HD100812
6 · The paper itself

Abstract

Current diagnostic criteria for polycystic ovary syndrome (PCOS) are based on expert opinion. This article reviews the rationale for and the limitations of these criteria as well as which criteria to use and when. The insights provided into PCOS pathogenesis by modern genetic analyses and the promise of objective data mining approaches for biologically relevant disease classification are discussed.

Indexed as

Polycystic Ovary SyndromeFemaleHumansDiagnostic criteriaDisease classificationHyperandrogenismPCOSPolycystic ovary syndrome

Identifiers

PMID33518179
PMCPMC7860982

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.