Evidence map›Paper›PMID 33519394›Full record

ArticleFrontiers in behavioral neuroscience2020

PsyCoP - A Platform for Systematic Semi-Automated Behavioral and Cognitive Profiling Reveals Gene and Environment Dependent Impairments of Tcf4 Transgenic Mice Subjected to Social Defeat.

Paul Volkmann, Marius Stephan, Sven Krackow, Niels Jensen, Moritz J Rossner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Mice lacking two alleles of the schizophrenia risk geneFrontiers in cellular neuroscience · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Paul VolkmannDepartment of Psychiatry and Psychotherapy, Laboratory of Molecular Neurobiology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Marius StephanDepartment of Psychiatry and Psychotherapy, Laboratory of Molecular Neurobiology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Sven KrackowInstitute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Niels JensenDepartment of Psychiatry and Psychotherapy, Laboratory of Molecular Neurobiology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Moritz J RossnerDepartment of Psychiatry and Psychotherapy, Laboratory of Molecular Neurobiology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DEUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, hundreds of risk genes associated with psychiatric disorders have been identified. These are thought to interact with environmental stress factors in precipitating pathological behaviors. However, the individual phenotypes resulting from specific genotype by environment (G×E) interactions remain to be determined. Toward a more systematic approach, we developed a novel standardized and partially automatized platform for systematic behavioral and cognitive profiling (PsyCoP). Here, we assessed the behavioral and cognitive disturbances in

Indexed as

gene × environment interactionintellectual disabilitiespsychiatrypsychosocial stressresearch domain criteriaschizophrenia

Identifiers

PMID33519394
PMCPMC7841301
OpenAlexW3118759982

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.