Evidence map›Paper›PMID 33520739›Full record

ArticleFrontiers in cellular and infection microbiology2020

Leaning Into the Bite: The piRNA Pathway as an Exemplar for the Genetic Engineering Need in Mosquitoes.

Vanessa M Macias, Umberto Palatini, Mariangela Bonizzoni, Jason L Rasgon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Vanessa M MaciasDepartment of Entomology, The Pennsylvania State University, University Park, PA, United States.
Umberto PalatiniDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Mariangela BonizzoniDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Jason L RasgonDepartment of Entomology, The Pennsylvania State University, University Park, PA, United States.
Pennsylvania State University · USUniversity of Pavia · IT

Funding

Hologenomic basis of WNV vector competence in Culex tarsalisR01AI150251 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI RASGON, JASON L · 2019 to 2024
$2.7M
Somatic and germline gene transduction in mosquitoesR01AI128201 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI Jason L Rasgon · 2017 to 2026
$2.4M
Wolbachia-induced enhancement of human arboviral pathogensR01AI116636 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI RASGON, JASON L · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI116636NIAID NIH HHS R01 AI128201NIAID NIH HHS R01 AI150251
6 · The paper itself

Abstract

The piRNA pathway is a specialized small RNA interference that in mosquitoes is mechanistically distant from analogous biology in the

Indexed as

CulicidaeAnimalsGenetic EngineeringMosquito VectorsRNA InterferenceRNA, Small InterferingRNA, Small Interferinggenetic engineering technologieshost-pathogen interactionsmosquito basic biologyPiwi-interacting RNAsvector-borne disease

Identifiers

PMID33520739
PMCPMC7840538
OpenAlexW3120099325

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.