Evidence map›Paper›PMID 33526125›Full record

ArticleJournal of cannabis research2020

The relationship of cannabis decriminalization in Colorado and cannabis use in individuals with alcohol use disorders.

Jeremy T Hua, Majid Afshar, Brendan J Clark, Elizabeth J Kovacs, Ellen L Burnham

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cannabis research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jeremy T HuaDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Majid AfsharDepartment of Medicine, Division of Pulmonary and Critical Care, Loyola University Chicago Health Sciences Campus, Chicago, IL, USA.
Brendan J ClarkDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, 12700 E. 19th St. C272, Aurora, CO, 80045, USA.
Elizabeth J KovacsDepartment of Surgery, Division of GI, Trauma, and Endocrine Surgery, University of Colorado School of Medicine, Aurora, CO, USA.
Ellen L BurnhamDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, 12700 E. 19th St. C272, Aurora, CO, 80045, USA. Ellen.burnham@cuanschutz.edu.ORCID http://orcid.org/0000-0002-9945-0284
University of Colorado Denver · USLoyola University Chicago · USUniversity of Colorado Anschutz Medical Campus · US

Funding

CoPARC: Colorado Pulmonary-Alcohol Research CollaborativeR24AA019661 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$673k
BLRD VA I01 BX004335NCATS NIH HHS UL1 TR002535NCRR NIH HHS UL1 RR025780NIAAA NIH HHS K23 AA024503NIAAA NIH HHS K23AA024503NIAAA NIH HHS R21 AA026295NIAAA NIH HHS R21AA026295NIAAA NIH HHS R24 AA019661NIAAA NIH HHS R24AA019661NIGMS NIH HHS R01 GM115257NIGMS NIH HHS R01GM115257
6 · The paper itself

Abstract

objectiveOver the past decade, cannabis use has become increasingly popular in states that include Colorado. During this time, alcohol use disorders (AUDs) and alcohol-related medical conditions have also been consistently recognized as public health problems with increasing prevalence in the state. Despite the widespread use of cannabis in Colorado, the epidemiology of cannabis use among those with AUDs has been poorly described. Therefore, we sought to examine cannabis use among individuals with likely AUDs and individuals with low-risk alcohol use during a time of major Colorado legislative changes before and after legalization of recreational cannabis in 2012.

methodsThis study was a secondary data analysis conducted with information from 303 participants (80% male) in the Denver, CO metropolitan enrolled between August 2007 and April 2016 for studies related to alcohol and lung health. Of these participants, 188 (62%) were completing inpatient alcohol detoxification with likely AUDs. All participants completed the Alcohol Use Disorder Identification Test (AUDIT) to establish their likelihood of an AUD, and all had information on current cannabis use assessed by questionnaire and urine toxicology testing.

resultsIndividuals with likely AUDs more commonly used cannabis compared to control participants (42% vs 27%, p = 0.007). In multiple logistic regression analyses, participant type (likely AUD versus control), tobacco smoking, and age were significantly associated with cannabis smoking; however, the year of participant enrollment was not. Adjusted odds for cannabis use among participants with likely AUDs were 2.97 (1.51-5.82), p = 0.002, while odds for cannabis use among tobacco smokers were 3.67 (1.94-6.93), p < 0.0001. Among control participants, tobacco smoking increased odds of cannabis use seven-fold.

conclusionsOur findings highlight the exceptionally high odds of cannabis use among individuals with likely AUDs undergoing alcohol detoxification at a Colorado treatment facility before and after legalization of recreational cannabis. Targeted investigations into the medical and psychiatric consequences of combined alcohol and cannabis use are urgently needed to define its health impact in these vulnerable individuals.

Indexed as

AlcoholismCannabisCodependencyDual useLegislationTobacco

Identifiers

PMID33526125
PMCPMC7819320
OpenAlexW3029716117

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.