Evidence map›Paper›PMID 33530452›Full record

ArticleBiomolecules2021

Transcriptome Analysis Reveals Altered Inflammatory Pathway in an Inducible Glial Cell Model of Myotonic Dystrophy Type 1.

Cuauhtli N Azotla-Vilchis, Daniel Sanchez-Celis, Luis E Agonizantes-Juárez, Rocío Suárez-Sánchez, J Manuel Hernández-Hernández, Jorge Peña, Karla Vázquez-Santillán, Norberto Leyva-García, Arturo Ortega, Vilma Maldonado and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  5. Article
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  7. Article
  8. Cellular Senescence and Aging in Myotonic Dystrophy.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Review
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Cuauhtli N Azotla-VilchisLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0002-3478-4427
Daniel Sanchez-CelisLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.
Luis E Agonizantes-JuárezLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.
Rocío Suárez-SánchezLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0002-5269-7124
J Manuel Hernández-HernándezDepartment of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados, CINVESTAV-IPN, Mexico City 07360, Mexico.ORCID 0000-0001-7624-9986
Jorge PeñaComputational and Integrative Genomics Laboratory, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.
Karla Vázquez-SantillánEpigenetics Laboratory, Instituto Nacional de Medicina Genomica, Mexico City 14610, Mexico.
Norberto Leyva-GarcíaLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.
Arturo OrtegaDepartment of Toxicology, Centro de Investigación y de Estudios Avanzados, CINVESTAV-IPN, Mexico City 07360, Mexico.ORCID 0000-0002-9594-8114
Vilma MaldonadoEpigenetics Laboratory, Instituto Nacional de Medicina Genomica, Mexico City 14610, Mexico.
Claudia RangelComputational and Integrative Genomics Laboratory, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.
Jonathan J MagañaLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0003-4399-4618
Bulmaro CisnerosDepartment of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados, CINVESTAV-IPN, Mexico City 07360, Mexico.
Oscar Hernández-HernándezLaboratory of Genomic Medicine, Department of Genetics, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0001-6388-2459
Instituto Nacional de Rehabilitación · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXNational Institute of Genomic Medicine · MXClaremont Graduate University · US

Funding

Consejo Nacional de Ciencia y Tecnología CB-2012-01/183697, CB258043 and CB258268
6 · The paper itself

Abstract

Myotonic dystrophy type 1 (DM1), the most frequent inherited muscular dystrophy in adults, is caused by the CTG repeat expansion in the 3'UTR of the

Indexed as

MutationTranscriptome3' Untranslated RegionsAlternative SplicingCell LineCell NucleusCentral Nervous SystemExonsGene Expression ProfilingGene Expression RegulationGenotypeHumansImmune SystemInflammationMyotonic DystrophyMyotonin-Protein Kinase3' Untranslated RegionsDMPK protein, humanMyotonin-Protein KinaseRNAgene expressioninducible cell modelsmicroarraysmyotonic dystrophy type 1RNA foci

Identifiers

PMID33530452
PMCPMC7910866
OpenAlexW3123235503

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.