Evidence map›Paper›PMID 33531433›Full record

ArticleDevelopment (Cambridge, England)2021

Retinoic acid production, regulation and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification.

Aditi Dubey, Jianshi Yu, Tian Liu, Maureen A Kane, Jean-Pierre Saint-Jeannet

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Anterior patterning genes induced by Zic1 are sensitive to retinoic acid and its metabolite, 4-oxo-RA.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aditi DubeyDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA.ORCID 0000-0002-1030-1347
Jianshi YuDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Tian LiuDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Maureen A KaneDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.ORCID 0000-0002-5525-9170
Jean-Pierre Saint-JeannetDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA jsj4@nyu.edu.ORCID 0000-0003-3259-2103
University of Maryland, Baltimore · USNew York University · US

Funding

Molecular control of cranial placode progenitor formationR01DE025806 · NIDCR · NEW YORK UNIVERSITY · PI SAINT-JEANNET, JEAN-PIERRE · 2016 to 2020
$2.0M
Molecular determinants of retinoid metabolism in embryonic tissuesR01HD077260 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI KANE, MAUREEN A, MOISE, ALEX RADU · 2014 to 2018
$1.6M
Local modulation of retinoic acid signaling in cranial placode formationF32DE027599 · NIDCR · NEW YORK UNIVERSITY · PI DUBEY, ADITI · 2018 to 2020
$193k
NICHD NIH HHS R01 HD077260NIDCR NIH HHS F32 DE027599NIDCR NIH HHS R01 DE025806
6 · The paper itself

Abstract

All paired sensory organs arise from a common precursor domain called the pre-placodal region (PPR). In

Indexed as

OrganogenesisAnimalsBody PatterningCytochrome P-450 Enzyme SystemEmbryo, NonmammalianGene Expression Regulation, DevelopmentalGene Knockdown TechniquesHomeodomain ProteinsImmunohistochemistryModels, BiologicalPhenotypeTranscription FactorsTretinoinXenopus laevisXenopus Proteinscytochrome P-450 26c protein, XenopusCytochrome P-450 Enzyme SystemHomeodomain ProteinsPitx2c protein, XenopusTranscription FactorsTretinoinXenopus ProteinsZic1 protein, XenopusDegradationPatterningPlacodeRetinoic acidXenopus

Identifiers

PMID33531433
PMCPMC7903997
OpenAlexW3128449495

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.