Evidence map›Paper›PMID 33532626›Full record

ArticleEndocrinology, diabetes & metabolism2021

Magnesium dietary intake and physical activity in Type 2 diabetes by gender in White, African-American and Mexican American: NHANES 2011-2014.

You Wu, Susmita Datta, Bert B Little, Maiying Kong

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

You WuGlobal Biostatistics Science Center for Design and Analysis Amgen Inc. Thousand Oaks CA USA.ORCID 0000-0003-4537-6530
Susmita DattaDepartment of Biostatistics, College of Public Health & Health Professions and College of Medicine University of Florida 2004 Mowry Rd Gainesville United States FL 32611-7450 USA.ORCID 0000-0002-7408-699X
Bert B LittleDepartment of Health Management and Systems Sciences School of Public Health and Information Sciences University of Louisville Louisville KY USA.ORCID 0000-0002-6485-4641
Maiying KongDepartment of Bioinformatics and Biostatistics School of Public Health and Information Sciences University of Louisville Louisville KY USA.ORCID 0000-0002-7313-9084
University of Louisville · USAmgen (United States) · USUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To analyse the causal relationships of nutrition intake and physical activity on haemoglobin A1c (HbA1C) in patients diagnosed with type 2 diabetes mellitus (T2DM) stratified by gender and ethnicity. Materials and Methods: An historical cohort of patients with diagnosed T2DM (n = 2831) was extracted from the National Health and Nutrition Examination Survey (NHANES) 2011-2014 public database, including but not limited to, measurements of physical activity, nutrition, body mass index (BMI) and HbA1c. Multivariate analyses and path analyses were employed to estimate the regression coefficients and path coefficients ( Results: A significant causal path from increased physical activity to increased magnesium (Mg) intake to decreased HbA1c was found. In addition, increased physical activity significantly decreased BMI, which further decreased HbA1c. These results varied by gender and ethnicity but were directionally consistent. Physical activity decreased HbA1c through BMI for males and through Mg intake for females. Mexican American decreased HbA1c through Mg intake, while non-Hispanic black had an increased HbA1c due to its ethnicity and through increased BMI. Conclusions: The beneficial effects of physical activity on decreased HbA1c were mediated through the increased Mg intake and decreased BMI. This aligned with recent investigations of the inverse causal association of Mg intake with insulin resistance and with decreased inflammation.

Indexed as

Datasets as TopicRacial GroupsSex CharacteristicsAdultAgedBody Mass IndexCohort StudiesDiabetes Mellitus, Type 2EatingExerciseFemaleGlycated HemoglobinHumansInsulin ResistanceMagnesium CompoundsMaleGlycated Hemoglobinhemoglobin A1c protein, humanMagnesium Compoundsmagnesium intakeNHANESpath analysisphysical activityT2DM

Identifiers

PMID33532626
PMCPMC7831210
OpenAlexW3108309042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.