Evidence map›Paper›PMID 33535610›Full record

ArticleInternational journal of molecular sciences2021

Phosphatidic Acid Stimulates Myoblast Proliferation through Interaction with LPA1 and LPA2 Receptors.

Ana Gomez-Larrauri, Patricia Gangoiti, Natalia Presa, Asier Dominguez-Herrera, Chiara Donati, Paola Bruni, Miguel Trueba, Antonio Gomez-Muñoz, Alberto Ouro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ana Gomez-LarrauriDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Patricia GangoitiDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Natalia PresaDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Asier Dominguez-HerreraDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Chiara DonatiDepartment of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale GB Morgagni 50, 50134 Firenze, Italy.
Paola BruniDepartment of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale GB Morgagni 50, 50134 Firenze, Italy.
Miguel TruebaDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Antonio Gomez-MuñozDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.
Alberto OuroDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48980 Bilbao, Spain.ORCID 0000-0003-4359-1704
University of the Basque Country · ESUniversity of Florence · IT

Funding

Departamento de Educación del Gobierno Vasco IT-1106-16Ministerio de Ciencia, Innovación y Universidades SAF2016-79695-R
6 · The paper itself

Abstract

Phosphatidic acid (PA) is a bioactive phospholipid capable of regulating key biological functions, including neutrophil respiratory burst, chemotaxis, or cell growth and differentiation. However, the mechanisms whereby PA exerts these actions are not completely understood. In this work, we show that PA stimulates myoblast proliferation, as determined by measuring the incorporation of [

Indexed as

AnimalsCell DifferentiationCell LineCell ProliferationChemotaxisDNALysophospholipidsMiceMyoblastsPhosphatidic AcidsPhosphatidylinositol 3-KinasesPhosphorylationProtein BindingReceptors, Lysophosphatidic AcidRNA, Small InterferingSignal TransductionDNAlysophosphatidic acidLysophospholipidsPhosphatidic AcidsPhosphatidylinositol 3-KinasesReceptors, Lysophosphatidic AcidRNA, Small Interferinglysophosphatidic acidlysophosphatidic acid receptorsmyoblast proliferationphosphatidic acid

Identifiers

PMID33535610
PMCPMC7867176
OpenAlexW3127547313

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.