Evidence map›Paper›PMID 33540792›Full record

ArticleInternational journal of molecular sciences2021

Stress Impairs Skin Barrier Function and Induces α2-3 Linked

John Benktander, Henrik Sundh, Kristina Sundell, Abarna V M Murugan, Vignesh Venkatakrishnan, János Tamás Padra, Jelena Kolarevic, Bendik Fyhn Terjesen, Marnix Gorissen, Sara K Lindén

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Identification of Novel Glycans in the Mucus Layer of Shark and Skate Skin.International journal of molecular sciences · 2023
    Article
  6. Review
  7. Virulence · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

John BenktanderDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, Medicinaregatan 9C, 405 30 Gothenburg, Sweden.
Henrik SundhDepartment of Biological and Environmental Sciences, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-1459-5450
Kristina SundellDepartment of Biological and Environmental Sciences, University of Gothenburg, 405 30 Gothenburg, Sweden.
Abarna V M MuruganDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, Medicinaregatan 9C, 405 30 Gothenburg, Sweden.
Vignesh VenkatakrishnanDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, Medicinaregatan 9C, 405 30 Gothenburg, Sweden.
János Tamás PadraDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, Medicinaregatan 9C, 405 30 Gothenburg, Sweden.
Jelena KolarevicNofima, Sjølsengen 22, 6600 Sunndalsøra, Norway.
Bendik Fyhn TerjesenCermaq Group AS, 0190 Oslo, Norway.
Marnix GorissenRadboud University, Institute for Water and Wetland Research, Department of Animal Ecology & Physiology, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
Sara K LindénDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, Medicinaregatan 9C, 405 30 Gothenburg, Sweden.ORCID 0000-0002-7751-9586
University of Gothenburg · SENofima · NORadboud University Nijmegen · NL

Funding

Norges Forskningsråd 233870/E40Norges Forskningsråd 237856/O30Svenska Forskningsrådet Formas 2016-05154_3Svenska Forskningsrådet Formas 2018-01419
6 · The paper itself

Abstract

The skin barrier consists of mucus, primarily comprising highly glycosylated mucins, and the epithelium. Host mucin glycosylation governs interactions with pathogens and stress is associated with impaired epithelial barrier function. We characterized Atlantic salmon skin barrier function during chronic stress (high density) and mucin

Indexed as

CrowdingAnimalsBiomarkersChromatography, LiquidGlycosylationHydrocortisoneMannitolMass SpectrometryMucinsMucusN-Acetylneuraminic AcidOxygenPolysaccharidesProtein Processing, Post-TranslationalSalmo salarSkinBiomarkersHydrocortisoneMannitolMucinsN-Acetylneuraminic AcidOxygenPolysaccharidesAtlantic salmonbarrier functionLiquid chromatography–mass spectrometrymucinO-glycanskinstressstress indicator

Identifiers

PMID33540792
PMCPMC7867331
OpenAlexW3128794074

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.