Evidence map›Paper›PMID 33545157›Full record

ReviewEuropean journal of pharmacology2021

COVID-19 infection and nanomedicine applications for development of vaccines and therapeutics: An overview and future perspectives based on polymersomes.

Mohammad A I Al-Hatamleh, Ma'mon M Hatmal, Walhan Alshaer, Engku Nur Syafirah E A Rahman, Manali Haniti Mohd-Zahid, Dina M Alhaj-Qasem, Chan Yean Yean, Iskandar Z Alias, Juhana Jaafar, Khalid Ferji and 4 more

Abstract readReview
In one paragraph

Review in European journal of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. The application of nanomedicine in clinical settings.Frontiers in bioengineering and biotechnology · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. The role of nanomedicine in COVID-19 therapeutics.Nanomedicine (London, England) · 2022
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mohammad A I Al-HatamlehDepartment of Immunology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia.
Ma'mon M HatmalDepartment of Medical Laboratory Sciences, Faculty of Applied Health Sciences, The Hashemite University, P.O. Box 330127, Zarqa, 13133, Jordan.
Walhan AlshaerCell Therapy Center (CTC), The University of Jordan, Amman, 11942, Jordan.
Engku Nur Syafirah E A RahmanDepartment of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia.
Manali Haniti Mohd-ZahidDepartment of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia.
Dina M Alhaj-QasemPrecision Medical Laboratory, Amman, 11954, Jordan.
Chan Yean YeanDepartment of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia; Hospital Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia.
Iskandar Z AliasDepartment of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia; Hospital Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia.
Juhana JaafarAdvanced Membrane Technology Research Centre (AMTEC), School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai, 81310, Johor, Malaysia.
Khalid FerjiUniversité de Lorraine, CNRS, LCPM, F-5400, Nancy, France.
Jean-Luc SixUniversité de Lorraine, CNRS, LCPM, F-5400, Nancy, France.
Vuk UskokovićTardigradeNano LLC, Irvine, CA, 92604, USA.
Hiroshi YabuWPI-Advanced Institute for Materials Research (AIMR), Tohoku University, 2-1-1, Katahira, Aoba-Ku, Sendai, 980-8577, Japan.
Rohimah MohamudDepartment of Immunology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia; Hospital Universiti Sains Malaysia, Kubang Kerian, 16150, Kelantan, Malaysia. Electronic address: rohimahm@usm.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which emerged in December 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic, took the world by surprise with an unprecedented public health emergency. Since this pandemic began, extraordinary efforts have been made by scientists to understand the pathogenesis of COVID-19, and to fight the infection by providing various preventive, diagnostic and treatment opportunities based on either novel hypotheses or past experiences. Despite all the achievements, COVID-19 continues to be an accelerating health threat with no specifically approved vaccine or therapy. This review highlights the recent advances in COVID-19 infection, with a particular emphasis on nanomedicine applications that can help in the development of effective vaccines or therapeutics against COVID-19. A novel future perspective has been proposed in this review based on utilizing polymersome nano-objects for effectively suppressing the cytokine storm, which may reduce the severity of COVID-19 infection.

Indexed as

COVID-19COVID-19 Drug TreatmentAntiviral AgentsDrug DevelopmentHumansNanomedicineSARS-CoV-2Viral VaccinesAntiviral AgentsViral Vaccines2019-nCoVCoronavirusCytokine stormNanomedicineSARS-CoV-2

Identifiers

PMID33545157
PMCPMC7857087

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.