Evidence map›Paper›PMID 33546364›Full record

ArticleInternational journal of molecular sciences2021

Distinctive Microbial Signatures and Gut-Brain Crosstalk in Pediatric Patients with Coeliac Disease and Type 1 Diabetes Mellitus.

Parul Singh, Arun Rawat, Bara Al-Jarrah, Saras Saraswathi, Hoda Gad, Mamoun Elawad, Khalid Hussain, Mohammed A. Hendaus, Wesam Al-Masri, Rayaz A Malik and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  7. Variations in gut microbiota in celiac disease patients: a systematic review.Gastroenterology and hepatology from bed to bench · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Parul SinghResearch Department, Sidra Medicine, Doha 26999, Qatar.ORCID 0000-0002-0438-3024
Arun RawatResearch Department, Sidra Medicine, Doha 26999, Qatar.
Bara Al-JarrahResearch Department, Sidra Medicine, Doha 26999, Qatar.
Saras SaraswathiDivision of Gastroenterology, Hepatology, and Nutrition, Sidra Medicine, Doha 26999, Qatar.ORCID 0000-0001-6473-1804
Hoda GadDepartment Medicine, Weill Cornell Medicine-Qatar, Doha 24144, Qatar.ORCID 0000-0002-8347-6623
Mamoun ElawadDivision of Gastroenterology, Hepatology, and Nutrition, Sidra Medicine, Doha 26999, Qatar.
Khalid HussainDivision of Endocrinology, Sidra Medicine, Doha 26999, Qatar.ORCID 0000-0002-5480-7112
Mohammed A. HendausDivision of General Pediatrics, Sidra Medicine, Doha 26999, Qatar.ORCID 0000-0001-9900-237X
Wesam Al-MasriDivision of Gastroenterology, Hepatology, and Nutrition, Sidra Medicine, Doha 26999, Qatar.
Rayaz A MalikDepartment Medicine, Weill Cornell Medicine-Qatar, Doha 24144, Qatar.ORCID 0000-0002-7188-8903
Souhaila Al KhodorResearch Department, Sidra Medicine, Doha 26999, Qatar.ORCID 0000-0003-4858-7130
Anthony K AkobengDivision of Gastroenterology, Hepatology, and Nutrition, Sidra Medicine, Doha 26999, Qatar.
Weill Cornell Medical College in Qatar · QAHamad bin Khalifa University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coeliac disease (CD) and Type 1 diabetes mellitus (T1DM) are immune-mediated diseases. Emerging evidence suggests that dysbiosis in the gut microbiome plays a role in the pathogenesis of both diseases and may also be associated with the development of neuropathy. The primary goal in this cross-sectional pilot study was to identify whether there are distinct gut microbiota alterations in children with CD (

Indexed as

BrainDysbiosisGastrointestinal MicrobiomeTrigeminal Nerve DiseasesAdolescentBacteroidetesCeliac DiseaseChildCorneaCross-Sectional StudiesDiabetes Mellitus, Type 1Escherichia coliHumansPilot ProjectsShigellachildrencoeliac diseasecorneal confocal microscopygut microbiotapediatric neuropathyT1DM

Identifiers

PMID33546364
PMCPMC7913584
OpenAlexW3126292069

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.