Evidence map›Paper›PMID 33547929›Full record

ArticleHeart and vessels2021

Effects of whole-body neuromuscular electrical stimulation device on hemodynamics, arrhythmia, and sublingual microcirculation.

Megumi Hoshiai, Kaori Ochiai, Yuma Tamura, Tomoki Tsurumi, Masato Terashima, Hajime Tamiya, Eikou Maeno, Satoshi Mizuguchi, Takashi Tomoe, Atsuhiko Kawabe and 7 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Heart and vessels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06188481 (Efficacy of Whole-body Electromyostimulation), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06188481 nacompletednot on this mapstarted 2024, after this paper: background citation

Efficacy of Whole-body Electromyostimulation (WB-EMS) Training on Glycemic Control in People With Prediabetes: a Randomized Controlled Pilot-study

TypeinterventionalSponsorUniversity Hospital TuebingenRan2024 to 2025Enrolled66ConditionsPre-diabetesArmswhole-body electromyostimulation training, activity tracker, evidence-based lifestyle education program
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Megumi Hoshiai *Department of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Kaori Ochiai *Department of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Yuma TamuraDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Tomoki TsurumiDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Masato TerashimaDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Hajime TamiyaDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Eikou MaenoDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Satoshi MizuguchiDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Takashi TomoeDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Atsuhiko KawabeDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Atsuko UemaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Asuka UenoDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Takushi SugiyamaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Yasuto HorieDepartment of Cardiology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Hiroyuki SugimuraDepartment of Cardiology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Ryousuke KoikeDepartment of Pulmonology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan.
Takanori YasuDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko, Tochigi, Japan. tyasu@dokkyomed.ac.jp.
Dokkyo Medical University · JP

Funding

Dokkyo Medical University, Young Investigator Award No.2018-23
6 · The paper itself

Abstract

Neuromuscular electrical stimulation has been used to treat cardiovascular diseases and other types of muscular dysfunction. A novel whole-body neuromuscular electrical stimulation (WB-NMES) wearable device may be beneficial when combined with voluntary exercises. This study aimed to investigate the safety and effects of the WB-NMES on hemodynamics, arrhythmia, and sublingual microcirculation. The study included 19 healthy Japanese volunteers, aged 22-33 years, who were not using any medication. Electrocardiogram (ECG), echocardiography, and blood sampling were conducted before a 20-min WB-NMES session and at 0 and 10 min after termination of WB-NMES. Their tolerable maximum intensity was recorded using numeric rating scale. Arrhythmia was not detected during neuromuscular electrical stimulation or during 10 min of recovery. Blood pressure, heart rate, left ventricular ejection fraction, and diastolic function remained unchanged; however, mild mitral regurgitation was transiently observed during WB-NMES in a single male participant. A decrease in blood glucose and an increase in blood lactate levels were observed, but no changes in blood fluidity, sublingual microcirculation, blood levels of noradrenaline, or oxidative stress were shown. WB-NMES is safe and effective for decreasing blood glucose and increasing blood lactate levels without changing the blood fluidity or microcirculation in healthy people.

Indexed as

AdultArrhythmias, CardiacElectric StimulationEquipment DesignFemaleHemodynamicsHumansMaleMicrocirculationMouth FloorTreatment OutcomeYoung AdultArrhythmiaMicrocirculationOxidative stressRheologyWhole-body neuromuscular electrical stimulation

Identifiers

PMID33547929
PMCPMC8093154
OpenAlexW3127513152

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.