Evidence map›Paper›PMID 33554279›Full record

ArticleArchives of toxicology2021

Intestinal and hepatic effects of iron oxide nanoparticles.

Linn Voss, Elisa Hoché, Valerie Stock, Linda Böhmert, Albert Braeuning, Andreas F Thünemann, Holger Sieg

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Archives of toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Linn VossGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Elisa HochéGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Valerie StockGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Linda BöhmertGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Albert BraeuningGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Andreas F ThünemannGerman Federal Institute for Material Research and Testing (BAM), Unter den Eichen 87, 12205, Berlin, Germany.ORCID 0000-0002-9883-6134
Holger SiegGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany. holger.sieg@bfr.bund.de.ORCID 0000-0002-0593-0173
Federal Institute for Risk Assessment · DEFederal Institute For Materials Research and Testing · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron oxide nanoparticles gain increasing attention due to their broad industrial use. However, safety concerns exist since their effects on human cells are still under investigation. The presence of iron oxide nanoparticles in the food pigment E172 has been shown recently. Here, we studied four iron oxide nanoparticles, one food pigment E172 and the ionic control FeSO

Indexed as

ApoptosisBiological TransportCaco-2 CellsCarcinoma, HepatocellularCell Line, TumorHumansIntestinesLiver NeoplasmsMagnetic Iron Oxide NanoparticlesMembrane Potential, MitochondrialReactive Oxygen SpeciesReactive Oxygen SpeciesCellular effectsIron oxide nanoparticlesNanoparticlesToxicityUptake and transport

Identifiers

PMID33554279
PMCPMC7904561
OpenAlexW3128016145

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.