Evidence map›Paper›PMID 33554446›Full record

ArticleChembiochem : a European journal of chemical biology2021

Arylphosphonate-Tethered Porphyrins: Fluorescence Silencing Speaks a Metal Language in Living Enterocytes*.

Claudia Keil, Julia Klein, Franz-Josef Schmitt, Yunus Zorlu, Hajo Haase, Gündoğ Yücesan

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. A 2,7-dichlorofluorescein derivative to monitor microcalcifications.Molecular systems design & engineering · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Claudia KeilTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.
Julia KleinTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.
Franz-Josef SchmittMartin-Luther-Universität Halle-Wittenberg, Department of Physics, von-Danckelmann-Platz 3, 06120, Halle/Saale, Germany.
Yunus ZorluDepartment of Chemistry, Faculty of Science, Gebze Technical University, 41400, Gebze-Kocaeli, Turkey.
Hajo HaaseTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.
Gündoğ YücesanTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.ORCID 0000-0002-5105-7280
Technische Universität Berlin · DEGebze Technical University · TRMartin Luther University Halle-Wittenberg · DE

Funding

DFG
6 · The paper itself

Abstract

We report the application of a highly versatile and engineerable novel sensor platform to monitor biologically significant and toxic metal ions in live human Caco-2 enterocytes. The extended conjugation between the fluorescent porphyrin core and metal ions through aromatic phenylphosphonic acid tethers generates a unique turn off and turn on fluorescence and, in addition, shifts in absorption and emission spectra for zinc, cobalt, cadmium and mercury. The reported fluorescent probes p-H

Indexed as

Caco-2 CellsCoordination ComplexesEnterocytesFluorescenceFluorescent DyesHumansMetals, HeavyOrganophosphonatesPorphyrinsCoordination ComplexesFluorescent DyesMetals, HeavyOrganophosphonatesPorphyrinsCaco-2fluorescence sensorshomeostasismetalstime-resolved fluorescence

Identifiers

PMID33554446
PMCPMC8252553
OpenAlexW3128593160

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.