Evidence map›Paper›PMID 33554855›Full record

ArticleeLife2021

Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia.

Laura Fontenas, Sarah Kucenas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Peripheral glia diversity.Journal of anatomy · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laura FontenasDepartment of Biology, University of Virginia, Charlottesville, United States.ORCID 0000-0003-0544-0147
Sarah KucenasDepartment of Biology, University of Virginia, Charlottesville, United States.ORCID 0000-0002-1950-751X
University of Virginia · US

Funding

Genetic Analysis of Glial Contribution to Peripheral Nervous System AssemblyR01NS072212 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2010 to 2019
$3.5M
Characterization of the cellular and molecular mechanisms that mediate glial tilingR01NS107525 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS072212NINDS NIH HHS R01 NS107525
6 · The paper itself

Abstract

During development, oligodendrocytes and Schwann cells myelinate central and peripheral nervous system axons, respectively, while motor exit point (MEP) glia are neural tube-derived, peripheral glia that myelinate axonal territory between these populations at MEP transition zones. From which specific neural tube precursors MEP glia are specified, and how they exit the neural tube to migrate onto peripheral motor axons, remain largely unknown. Here, using zebrafish, we found that MEP glia arise from lateral floor plate precursors and require

Indexed as

NeurogenesisAnimalsAxonsForkhead Transcription FactorsMyelin SheathNeural CrestNeural TubeNeurogliaPeripheral Nervous SystemSpinal CordZebrafishZebrafish ProteinsForkhead Transcription Factorsfoxd3 protein, zebrafishZebrafish Proteinsdevelopmental biologymotor exit point gliamyelinating glianeural precursorsneuroscienceradial gliatransition zonezebrafish

Identifiers

PMID33554855
PMCPMC7886336
OpenAlexW3128471769

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.