Evidence map›Paper›PMID 33559028›Full record

ArticleIn vitro cellular & developmental biology. Animal2021

Copper toxicity of inflection point in human intestinal cell line Caco-2 dissected: influence of temporal expression patterns.

Joanne Keenan, Paula Meleady, Charles O'Doherty, Michael Henry, Martin Clynes, Karina Horgan, Richard Murphy, Finbarr O'Sullivan

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joanne KeenanNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland. joanne.keenan@dcu.ie.ORCID http://orcid.org/0000-0003-0047-4268
Paula MeleadyNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland.
Charles O'DohertyNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland.
Michael HenryNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland.
Martin ClynesNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland.
Karina HorganAlltech, Dunboyne, Meath, Ireland.
Richard MurphyAlltech, Dunboyne, Meath, Ireland.
Finbarr O'SullivanNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, 09 W6Y4, Ireland.
Dublin City University · IEAlltech (Ireland) · IE

Funding

Enterprise Ireland IP/2015/0375
6 · The paper itself

Abstract

We previously described a non-monotonic dose response curve at low copper concentrations where 3.125 μM CuSO

Indexed as

Caco-2 CellsCell CountCell SurvivalCopperGlutathioneHumansIntestinesProtein UnfoldingProteomicsReproducibility of ResultsTime FactorsCopperGlutathioneCaco-2CopperGranulinsProteomicsZFAND2A

Identifiers

PMID33559028
OpenAlexW3126552101

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.