Evidence map›Paper›PMID 33560713›Full record

ArticleMedical care2021

Geographic Variation of Statin Use Among US Nursing Home Residents With Life-limiting Illness.

Deborah S Mack, Jonggyu Baek, Jennifer Tjia, Kate L Lapane

Open access · greenAbstract read
In one paragraph

Article in Medical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Deborah S MackDivision of Epidemiology, Department of Population and Quantitative Health Sciences.
Jonggyu BaekDivision of Biostatistics and Health Services Research, Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA.
Jennifer TjiaDivision of Epidemiology, Department of Population and Quantitative Health Sciences.
Kate L LapaneDivision of Epidemiology, Department of Population and Quantitative Health Sciences.
Quantitative BioSciences · USUniversity of Massachusetts Chan Medical School · US

Funding

SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
Longitudinal Patterns of Symptoms, Medication and Hospice Use in Nursing Home Residents Approaching End of LifeK24AG068300 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TJIA, JENNIFER · 2020 to 2024
$949k
Use and safety of statins among nursing home residents with life-limiting illness in the United StatesR36HS026840 · AHRQ · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MACK, DEBORAH · 2019 to 2019
$43k
AHRQ HHS R36 HS026840NCATS NIH HHS TL1 TR001454NCATS NIH HHS UL1 TR001086NIA NIH HHS K24 AG068300
6 · The paper itself

Abstract

backgroundMedically compromised nursing home residents continue to be prescribed statins, despite questionable benefits.

objectiveTo describe regional variation in statin use among residents with life-limiting illness. RESEARCH

designCross-sectional study using 2016 Minimum Data Set 3.0 assessments linked to Medicare administrative data and health service utilization area resource files.

settingNursing homes (n=14,147) within hospital referral regions (n=306) across the United States. SUBJECTS: Long-stay residents (aged 65 y and older) with life-limiting illness (eg, serious illness, palliative care, or prognosis <6 mo to live) (n=361,170). MEASURES: Prevalent statin use was determined by Medicare Part D claims. Stratified by age (65-75, 76 y or older), multilevel logistic models provided odds ratios with 95% confidence intervals.

resultsStatin use was prevalent (age 65-75 y: 46.0%, 76 y or more: 31.6%). For both age groups, nearly all resident-level variables evaluated were associated with any and high-intensity statin use and 3 facility-level variables (ie, higher proportions of Black residents, skilled nursing care provided, and average number of medications per resident) were associated with increased odds of statin use. Although in residents aged 65-75 years, no associations were observed, residents aged 76 years or older located in hospital referral regions (HRRs) with the highest health care utilization had higher odds of statin use than those in nursing homes in HRRs with the lowest health care utilization.

conclusionsOur findings suggest extensive geographic variation in US statin prescribing across HRRs, especially for those aged 76 years or older. This variation may reflect clinical uncertainty given the largely absent guidelines for statin use in nursing home residents.

Indexed as

Clinical Decision-MakingGeography, MedicalAgedAged, 80 and overAge FactorsCross-Sectional StudiesDrug PrescriptionsFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMedicareNursing HomesPatient Acceptance of Health CarePractice Patterns, Physicians'United StatesHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID33560713
PMCPMC8791012
OpenAlexW3126664169

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.