Evidence map›Paper›PMID 33563655›Full record

Trial reportDiabetes care2021

Remote Continuous Glucose Monitoring With a Computerized Insulin Infusion Protocol for Critically Ill Patients in a COVID-19 Medical ICU: Proof of Concept.

Georgia M Davis, Eileen Faulds, Tara Walker, Debbie Vigliotti, Marina Rabinovich, Joi Hester, Limin Peng, Barbara McLean, Patricia Hannon, Norma Poindexter and 8 more

Registry-linked trialOpen access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07769138 (Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07769138 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM)

TypeobservationalSponsorImperial College Healthcare NHS TrustRan2026 to 2028Enrolled70ConditionsType 1 Diabetes, Type 2 Diabetes Treated With Insulin, Hyperglycemia, Intensive Care (ICU)ArmsDexcom G7, ViewsEMR telemetry
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Glucocorticoid-Induced Hyperglycemia Including Dexamethasone-Associated Hyperglycemia in COVID-19 Infection: A Systematic Review.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Pooled it
  3. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Continuous Glucose Monitoring-Guided Insulin Infusion in Critically Ill Patients Promotes Safety, Improves Time Efficiency, and Enhances Provider Satisfaction.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. [Current Status of Research on COVID-19 Patients With Concomitant Hyperglycemia and the Management Strategies of Hyperglycemia].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Georgia M DavisDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Eileen FauldsDivision of Endocrinology, The Ohio State University, Columbus, OH.ORCID 0000-0003-2315-1146
Tara WalkerInformation Technology, Grady Health System, Atlanta, GA.
Debbie VigliottiDepartment of Pharmacy, Grady Health System, Atlanta, GA.
Marina RabinovichDepartment of Pharmacy, Grady Health System, Atlanta, GA.
Joi HesterDepartment of Medicine, Morehouse School of Medicine, Atlanta, GA.
Limin PengDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA.
Barbara McLeanDivision of Critical Care, Grady Health System, Atlanta, GA.
Patricia HannonDivision of Critical Care, Grady Health System, Atlanta, GA.
Norma PoindexterDivision of Critical Care, Grady Health System, Atlanta, GA.
Petrena SaundersDivision of Critical Care, Grady Health System, Atlanta, GA.
Citlalli Perez-GuzmanDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Seema S TekwaniDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Emory University School of Medicine, Atlanta, GA.
Greg S MartinDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Emory University School of Medicine, Atlanta, GA.
Guillermo UmpierrezDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-3252-5026
Shivani AgarwalFleischer Institute for Diabetes and Metabolism, New York Regional Center for Diabetes Translational Research, Albert Einstein College of Medicine, Bronx, NY.
Kathleen DunganDivision of Endocrinology, The Ohio State University, Columbus, OH.ORCID 0000-0003-1289-1595
Francisco J PasquelDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA fpasque@emory.edu.ORCID 0000-0002-3845-6703
Emory University · USGrady Health System · USThe Ohio State University · USAlbert Einstein College of Medicine · USMorehouse School of Medicine · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Identifying and Reducing Disparities in Outcomes Among Economically Vulnerable and Minority Young Adults with Type 1 DiabetesK23DK115896 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AGARWAL, SHIVANI · 2018 to 2022
$988k
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery PatientsK23GM128221 · NIGMS · EMORY UNIVERSITY · PI PASQUEL, FRANCISCO J · 2018 to 2022
$957k
Perioperative Stress Hyperglycemia in General and Vascular Surgery PatientsK23DK122199 · NIDDK · EMORY UNIVERSITY · PI DAVIS, GEORGIA M · 2020 to 2024
$891k
NCATS NIH HHS UL1 TR002378NIDDK NIH HHS K23 DK115896NIDDK NIH HHS K23 DK122199NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P30 DK111024NIGMS NIH HHS K23 GM128221
6 · The paper itself

Abstract

objectiveThe use of remote real-time continuous glucose monitoring (CGM) in the hospital has rapidly emerged to preserve personal protective equipment and reduce potential exposures during coronavirus disease 2019 (COVID-19). RESEARCH DESIGN AND

methodsWe linked a hybrid CGM and point-of-care (POC) glucose testing protocol to a computerized decision support system for continuous insulin infusion and integrated a validation system for sensor glucose values into the electronic health record. We report our proof-of-concept experience in a COVID-19 intensive care unit.

resultsAll nine patients required mechanical ventilation and corticosteroids. During the protocol, 75.7% of sensor values were within 20% of the reference POC glucose with an associated average reduction in POC of 63%. Mean time in range (70-180 mg/dL) was 71.4 ± 13.9%. Sensor accuracy was impacted by mechanical interferences in four patients.

conclusionsA hybrid protocol integrating real-time CGM and POC is helpful for managing critically ill patients with COVID-19 requiring insulin infusion.

Indexed as

COVID-19COVID-19 Drug TreatmentDiabetes ComplicationsInsulin Infusion SystemsRemote Sensing TechnologyAgedAged, 80 and overAlgorithmsBlood GlucoseBlood Glucose Self-MonitoringCritical IllnessEquipment and SuppliesFemaleHumansInsulinIntensive Care UnitsBlood GlucoseInsulin

Identifiers

PMID33563655
PMCPMC7985417
OpenAlexW3126263986

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.