Once-Weekly Semaglutide in Adults with Overweight or Obesity.

What the trial testedrandomised · 1,961 people · 2021

Randomised comparison

−12.4percentage points−13.4 to −11.5

As reported

difference −12.4 percentage points, 95% CI −13.4 to −11.5

Randomised comparison

−12.7kg−13.7 to −11.7

As reported

difference −12.7 kg, 95% CI −13.7 to −11.7

the abstract, start to end

… for an estimated treatment difference of -12.4 percentage points (95% …

… group (estimated treatment difference, -12.7 kg; 95% CI, -13.7 to -11.7).

← favours treatmentfavours comparator →

could be chance

Body weight & composition

−12.4−13.4 to −11.5

Body weight & composition

−12.7−13.7 to −11.7

GLP-1 receptor agonistsBody weight & composition

GLP-1 receptor agonists × body weight & compositionhelps?replicated

unlikelylikely

0.900.90 without it

← favours treatmentfavours comparator →

this papermore certainless certain

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2021

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2026

this paperpooled ittrialcites it