Evidence map›Paper›PMID 33578781›Full record

ArticleAntioxidants (Basel, Switzerland)2021

FK866 Protects Human Dental Pulp Cells against Oxidative Stress-Induced Cellular Senescence.

Chang Youp Ok, Sera Park, Hye-Ock Jang, Takashi Takata, Ok-Hee Lee, Moon-Kyoung Bae, Soo-Kyung Bae

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. MnOMaterials today. Bio · 2026
    Article
  2. Review
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  11. mActa biochimica et biophysica Sinica · 2023
    Review
  12. Article
  13. Article
  14. The Potential of Senescence as a Target for Developing Anticancer Therapy.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Oxidative Stress and Cell Senescence Process.Antioxidants (Basel, Switzerland) · 2022
    Article
  18. Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chang Youp OkDepartment of Dental Pharmacology, School of Dentistry, Education and Research Team for Life Science on Dentistry, Pusan National University, Yangsan 50612, Korea.ORCID 0000-0001-9633-714X
Sera ParkDepartment of Dental Pharmacology, School of Dentistry, Education and Research Team for Life Science on Dentistry, Pusan National University, Yangsan 50612, Korea.
Hye-Ock JangDepartment of Dental Pharmacology, School of Dentistry, Education and Research Team for Life Science on Dentistry, Pusan National University, Yangsan 50612, Korea.
Takashi TakataTokuyama University, Shunan, Yamaguchi 745-8566, Japan.
Ok-Hee LeeDepartment of Biomedical Science, CHA University, Gyeonggi-do 13488, Korea.
Moon-Kyoung BaePeriodontal Disease Signaling Network Research Center, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
Soo-Kyung BaeDepartment of Dental Pharmacology, School of Dentistry, Education and Research Team for Life Science on Dentistry, Pusan National University, Yangsan 50612, Korea.
Pusan National University · KRCHA University · KRShunan University · JP

Funding

the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) NRF-2018R1A5A2023879
6 · The paper itself

Abstract

FK866 possesses various functional properties, such as anti-angiogenic, anti-cancer, and anti-inflammatory activities. We previously demonstrated that premature senescence of human dental pulp cells (hDPCs) was induced by hydrogen peroxide (H

Indexed as

human dental pulp cellshydrogen peroxideinflammationNF-κBreactive oxygen speciesSASP factorssenescencetelomere damage

Identifiers

PMID33578781
PMCPMC7916510
OpenAlexW3127242517

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.