Evidence map›Paper›PMID 33578971›Full record

ArticleBiomolecules2021

Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid.

Lianne R de Haan, Joanne Verheij, Rowan F van Golen, Verena Horneffer-van der Sluis, Matthew R Lewis, Ulrich H W Beuers, Thomas M van Gulik, Steven W M Olde Damink, Frank G Schaap, Michal Heger and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Lianne R de HaanJiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang 314001, China.
Joanne VerheijDepartment of Pathology, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Rowan F van GolenDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Verena Horneffer-van der SluisNational Phenome Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
Matthew R LewisNational Phenome Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
Ulrich H W BeuersDepartment of Gastroenterology & Hepatology and Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.
Thomas M van GulikDepartment of Surgery, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Steven W M Olde DaminkDepartment of Surgery & NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.
Frank G SchaapDepartment of Surgery & NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-1597-572X
Michal HegerJiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang 314001, China.
Pim B OlthofDepartment of Surgery, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLImperial College London · GBUniversity Medical Center · USErasmus MC · NLJiaxing University · CNLeiden University Medical Center · NLUtrecht University · NL

Funding

Grant for Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics 12.2019KWF Kankerbestrijding 10666Medical Research Council MC_PC_12025Zhejiang Provincial Foreign Expert Program Grant 12.2018Zhejiang Provincial Key Natural Science Foundation of China Z20H160031
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBile Acids and SaltsBile DuctsCell ProliferationChenodeoxycholic AcidCholestasisHumansIndocyanine GreenLiverLiver Function TestsLiver RegenerationMaleOrgan SizeRatsRats, WistarReceptor, Farnesoid X-ActivatedBile Acids and SaltsChenodeoxycholic AcidIndocyanine Greenobeticholic acidReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearTechnetiumbasolateral and canalicular transportersbile acid metabolismbile duct obstructionbile saltsbiliary obstructionliver regenerationpartial hepatectomypharmacological intervention

Identifiers

PMID33578971
PMCPMC7916678
OpenAlexW3127724386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.