Evidence map›Paper›PMID 33579693›Full record

ArticleBiology open2021

Monitoring

Chance E Jones, Susan L Forsburg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Diploidy confers genomic instability inbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Characterization of DNA-PK-Bound End Fragments Using GLASS-ChIP.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chance E JonesProgram in Molecular & Computational Biology, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0003-3926-6028
Susan L ForsburgProgram in Molecular & Computational Biology, University of Southern California, Los Angeles, CA 90089, USA Forsburg@usc.edu.ORCID 0000-0002-4895-8598

Funding

Mechanisms linking replication stress to genome instability in fission yeastR35GM118109 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2016 to 2025
$7.1M
CBI: Chemistry Biology InterfaceT32GM118289 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2016 to 2020
$1.2M
NIGMS NIH HHS R35 GM118109NIGMS NIH HHS T32 GM118289
6 · The paper itself

Abstract

Studies of genome stability have exploited visualization of fluorescently tagged proteins in live cells to characterize DNA damage, checkpoint, and repair responses. In this report, we describe a new tool for fission yeast, a tagged version of the end-binding protein Pku70 which is part of the KU protein complex. We compare Pku70 localization to other markers upon treatment to various genotoxins, and identify a unique pattern of distribution. Pku70 provides a new tool to define and characterize DNA lesions and the repair response.

Indexed as

DNA DamageGenome, FungalGenomic InstabilityDNA-Binding ProteinsDNA RepairFluorescent Antibody TechniqueProtein BindingProtein TransportSchizosaccharomycesSchizosaccharomyces pombe ProteinsTime-Lapse ImagingDNA-Binding ProteinsSchizosaccharomyces pombe ProteinsDNA damageFission yeastGenome stabilityKuMicroscopy

Identifiers

PMID33579693
PMCPMC7904001

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.