Evidence map›Paper›PMID 33582279›Full record

ArticleAnnals of epidemiology2021

Cumulative employment intensity and complexity across the life course and cognitive function in later life among European women and men.

Karra Greenberg, Sarah Burgard

Abstract read
In one paragraph

Article in Annals of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The social environment and cognitive aging over the life course: laying out critical concepts and research gaps.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karra GreenbergInstitute for Research on Women and Gender, University of Michigan, Ann Arbor, MI; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI. Electronic address: karrag@umich.edu.
Sarah BurgardPopulation Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI; Department of Sociology, University of Michigan, Ann Arbor, MI.

Funding

TRAINING IN THE DEMOGRAPHY OF AGINGT32AG000221 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sarah A. Burgard · 1992 to 2026
$15.3M
Population Studies Center Infrastructure GrantR24HD041028 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SMOCK, PAMELA J. · 2001 to 2016
$13.2M
Scientific/Technical CoreP2CHD041028 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sarah A. Burgard · 2017 to 2026
$6.5M
Economics and Demography of Aging TrainingT32AG033533 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BIANCHI, SUZANNE M., COSTA, DORA L · 2011 to 2015
$1.3M
NIA NIH HHS T32 AG000221NIA NIH HHS T32 AG033533NICHD NIH HHS P2C HD041028NICHD NIH HHS R24 HD041028
6 · The paper itself

Abstract

purposeRelatively little is known about how working-age life course cumulative exposure to employment intensity and job complexity informs older-age cognitive function. We investigate these associations, separately for men and women, and net of known confounders.

methodsUsing retrospective lifetime employment histories of Europeans born 1923-1959 (2004-2009, N = 22 266), we calculate cumulative working-age exposure to nonemployment, full-time and part-time employment, and a professional occupation. In gender-stratified linear regression models, these indicators predict cognitive function score based on the DemTect scale and Mini Mental State Exam.

resultsNonemployment ≥25% of the working life course was associated with poorer cognitive function for men by -0.43 points (95% CI = -0.79, -0.06) on a 19-point scale. Women's full-time employment, even if <25% of the working lifetime, was associated with a cognitive advantage over never-employment by 0.60 points (95% CI = 0.17, 1.02). Compared to predominantly nonprofessionally employed men, those working professionally for ≥75% of the life course had better cognition by 0.38 points (95% CI = 0.16, 0.60).

conclusionsThis paper provides novel evidence that older-age cognitive functioning is associated with cumulative exposure to both employment intensity and complexity, but that these relationships vary by sex.

Indexed as

CognitionEmploymentFemaleHumansMaleOccupationsRetrospective StudiesCognitive reserveemploymentlife historymen's healthwomen's health

Identifiers

PMID33582279
PMCPMC8513811

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.