Evidence map›Paper›PMID 33584144›Full record

ArticleJournal of medical biochemistry2021

Study on the correlation between urinary retinol-binding protein and nonalcoholic fatty liver disease.

Chuang Li, Weiwei Kong, Lixia Kang, Tiehan Zhang, Weiqun Zhang, Weidong Wang

Abstract read
In one paragraph

Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuang LiXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.
Weiwei KongXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.
Lixia KangXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.
Tiehan ZhangXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.
Weiqun ZhangXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.
Weidong WangXinxiang Medical University, The Third Affiliated Hospital, Department of Laboratory Medicine, Xinxiang, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonalcoholic fatty liver disease (NAFLD) affects human health worldwide. Our objective was to explore the correlation between urinary retinol-binding protein (URBP) and NAFLD.

methodsThis cross-sectional study included 445 NAFLD patients and 911 healthy controls. The URBP level and other parameters were measured.

resultsThe URBP level (expressed by the RBP/creatinine ratio) was higher in the NAFLD patients compared with the non-NAFLD patients. The urinary RBP/creatinine ratio was an independent risk factor for NAFLD after univariate and multivariate regression analysis, with the or values of 2.271 (1.795-2.872, P < 0.001) and 2.338 (1.775-3.080, P < 0.001), respectively. The prevalence of the urinary RBP/creatinine ratio (groups 1, 2, 3, 4) was 20.0%, 17.3%, 27.3%, and 35.4%, respectively (P < 0.001), and the prevalence of NAFLD in the high urinary RBP/creatinine ratio group was significantly higher than that in the low urinary RBP/creatinine ratio group.

conclusionsOur results revealed that the urinary RBP/creatinine ratio was an independent risk factor for NAFLD.

Indexed as

nonalcoholic fatty liver diseaserenal injuryretinol-binding protein

Identifiers

PMID33584144
PMCPMC7857848

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.