Evidence map›Paper›PMID 33584697›Full record

ReviewFrontiers in immunology

Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective.

Santosh V Suryavanshi, Igor Kovalchuk, Olga Kovalchuk

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

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  16. Chemical Profiling of Polyphenolic Fraction ofPlants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Santosh V SuryavanshiDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB, Canada.
Igor KovalchukDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB, Canada.
Olga KovalchukDepartment of Biological Sciences, University of Lethbridge, Lethbridge, AB, Canada.
University of Lethbridge · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect microbial materials, sterile inflammatory insults, and certain host-derived elements. Inflammasomes, once activated, promote caspase-1-mediated maturation and secretion of pro-inflammatory cytokines, interleukin (IL)-1β and IL-18, leading to pyroptosis. Current advances in inflammasome research support their involvement in the development of chronic inflammatory disorders in contrast to their role in regulating innate immunity. Cannabis (marijuana) is a natural product obtained from the

Indexed as

Anti-Inflammatory AgentsCannabinoidsCOVID-19HumansInflammasomesSARS-CoV-2Anti-Inflammatory AgentsCannabinoidsInflammasomescannabidiolcannabinoidsDelta-9 tetrahydrocannabinolinflammasomeinflammasome signalingpro-inflammatory cytokines

Identifiers

PMID33584697
PMCPMC7876066
OpenAlexW3128642997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.