Evidence map›Paper›PMID 33589569›Full record

Trial reportAging2021

The joint effect of energy reduction with calcium supplementation on the risk factors of type 2 diabetes in the overweight population: a two-year randomized controlled trial.

Wei Wei, Wenbo Jiang, Wenbo Gu, Huanyu Wu, Haiyang Jiang, Guili Li, Qingrao Song, Jiaxin Huang, Xuanyang Wang, Lulu Wang and 3 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Wei WeiDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Wenbo JiangDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Wenbo GuDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Huanyu WuDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Haiyang JiangDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Guili LiDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Qingrao SongDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Jiaxin HuangDepartment of Postgraduate, The Third Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Xuanyang WangDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Lulu WangDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Changhao SunDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Tianshu HanDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Ying LiDepartment of Nutrition and Food Hygiene, College of Public Health, Harbin Medical University, Harbin 150081, Heilongjiang Province, P. R. China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both excessive energy intake and low calcium intake are inversely associated with the aging-related diseases, particularly for type 2 diabetes mellitus(T2DM). This study examined whether energy reduction coupled with calcium supplementation aided in the prevention of T2DM among the overweight population. A randomized controlled trial(RCT) of 1021 overweight participants was performed, in which participants were randomly assigned to 4 groups: 1) energy-reduction group(ERG), 2) calcium supplementation group(CSG), 3) energy-reduction with calcium supplementation group(ER-CSG), 4) control group(CG). Nutritional habits, anthropometric and diabetes-related indicators were measured at baseline and each follow-up time. To analyze the separate effects of dietary energy reduction and calcium supplementation, ERG and ER-CSG were integrated into ERGs. Similarly, CSG and ER-CSG were integrated into CSGs. Compared to the non-energy-reduction groups(NERGs), ERGs had lower values of ΔBMI(-0.9kg/m

Indexed as

AdultBlood GlucoseCalciumCalcium-Regulating Hormones and AgentsDiabetes Mellitus, Type 2Dietary SupplementsDiet, ReducingFemaleGlycated HemoglobinHumansInsulin ResistanceMaleMiddle AgedOverweightPatient ComplianceBlood GlucoseCalciumCalcium-Regulating Hormones and AgentsGlycated Hemoglobinhemoglobin A1c protein, humancalcium supplementationenergy reductionjoint effectRCTT2DM

Identifiers

PMID33589569
PMCPMC7950291
OpenAlexW3129677789

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.