Evidence map›Paper›PMID 33594316›Full record

ArticleAmerican journal of translational research2021

Berberine protects human and rat cardiomyocytes from hypoxia/reoxygenation-triggered apoptosis.

Haiyan Yang, Xu Shang, Guoqing Zhong, Liangli Hong, Zhi Li, Wanling Zhuang, Jidong Cheng

RetractedOpen access · greenAbstract readRetracted Publication
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Haiyan YangThe First Affiliated Hospital of Shantou University Medical College & Laboratory of Molecular Cardiology & Laboratory of Molecular Imaging Shantou 515041, China.
Xu ShangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong Shantou 515041, China.
Guoqing ZhongShantou University Medical College Shantou 515041, China.
Liangli HongThe First Affiliated Hospital of Shantou University Medical College Shantou 515041, China.
Zhi LiThe Second Affiliated Hospital of Shantou University Medical College Shantou 515041, China.
Wanling ZhuangThe First Affiliated Hospital of Shantou University Medical College Shantou 515041, China.
Jidong ChengSchool Medical, Xiamen University Shantou 515041, China.
Shantou University · CNFirst Affiliated Hospital of Shantou University Medical College · CNShantou University Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Berberine (BBR) confers potential cardioprotective effects. However, the relevant mechanisms underlying its regulation of cardiomyocyte survival following hypoxia/reoxygenation (H/R) treatment remain unknown. The present study investigated whether BBR could protect H/R by suppressing apoptosis and explored how TGF-β/Smad4 signaling pathway influenced H/R

Indexed as

apoptosisBBRcardiomyocyteshypoxia/reoxygenationTGF-β/smad4 pathway

Identifiers

PMID33594316
PMCPMC7868847
OpenAlexW3131438184

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.