Evidence map›Paper›PMID 33597294›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

A specific basal body linker protein provides the connection function for basal body inheritance in trypanosomes.

De-Hua Lai, Flavia Moreira-Leite, Zhi-Shen Xu, Jiong Yang, Keith Gull

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Cell cycle ofCurrent zoology · 2026
    Article
  2. Single p197 molecules of the mitochondrial genome segregation system ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

De-Hua LaiCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, 510275 Guangzhou, People's Republic of China; laidehua@mail.sysu.edu.cn.ORCID 0000-0002-4709-1507
Flavia Moreira-LeiteDepartment of Biological and Medical Sciences, Oxford Brookes University, Oxford OX3 0BP, United Kingdom.ORCID 0000-0001-5691-140X
Zhi-Shen XuCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, 510275 Guangzhou, People's Republic of China.
Jiong YangCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, 510275 Guangzhou, People's Republic of China.ORCID 0000-0003-3967-8639
Keith GullSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0001-6954-9569
Sun Yat-sen University · CNOxford Brookes University · GBUniversity of Oxford · GB

Funding

Wellcome TrustWellcome Trust 104627/Z/14/ZWellcome Trust WT066839MA
6 · The paper itself

Abstract

Centrioles and basal bodies (CBBs) are found in physically linked pairs, and in mammalian cells intercentriole connections (G1-G2 tether and S-M linker) regulate centriole duplication and function. In trypanosomes BBs are not associated with the spindle and function in flagellum/cilia nucleation with an additional role in mitochondrial genome (kinetoplast DNA [kDNA]) segregation. Here, we describe BBLP, a BB/pro-BB (pBB) linker protein in

Indexed as

Basal BodiesCytoskeletonDNA, KinetoplastFlagellaProtozoan ProteinsRNA InterferenceTrypanosoma brucei bruceiDNA, KinetoplastProtozoan Proteinsbasal bodiesBBLPcell cyclecentrioleslinker

Identifiers

PMID33597294
PMCPMC7923635
OpenAlexW3131522077

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.