Evidence map›Paper›PMID 33612680›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Baseline Urinary Angiotensinogen Excretion Predicts Deterioration of the Kidney Function in Patients with Chronic Kidney Disease.

Sayaka Ishigaki, Naro Ohashi, Taro Aoki, Takashi Matsuyama, Shinsuke Isobe, Taichi Sato, Tomoyuki Fujikura, Akihiko Kato, Hideo Yasuda

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sayaka IshigakiBlood Purification Unit, Hamamatsu University School of Medicine, Japan.
Naro OhashiInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Taro AokiInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Takashi MatsuyamaInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Shinsuke IsobeInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Taichi SatoInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Tomoyuki FujikuraInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Akihiko KatoBlood Purification Unit, Hamamatsu University School of Medicine, Japan.
Hideo YasudaInternal Medicine 1, Hamamatsu University School of Medicine, Japan.
Hamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective The intrarenal renin-angiotensin system (RAS) is activated in patients with chronic kidney disease (CKD), and urinary angiotensinogen (AGT) levels, a surrogate marker of the intrarenal RAS activation, are associated with blood pressure (BP) and urinary albumin excretion. In addition, it has been shown that changes in urinary AGT levels correlate with annual changes in the estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes and that elevated levels of urinary AGT in type 2 diabetic patients with albuminuria are a high-risk factor for worsening renal and cardiovascular complications. However, whether or not baseline urinary AGT levels predict deterioration of the kidney function in all patients with CKD is unclear. Methods We recruited 62 patients with CKD whose eGFR was >15 mL/min/1.73 m

Indexed as

Diabetes Mellitus, Type 2Renal Insufficiency, ChronicAngiotensinogenHumansKidneyRenin-Angiotensin SystemAngiotensinogenchronic kidney diseaseintrarenal renin-angiotensin systemrenal prognosisurinary angiotensinogen

Identifiers

PMID33612680
PMCPMC8355400
OpenAlexW3130434294

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.