ArticlePulmonary circulation
Long-term outcomes of pregnant women with pulmonary hypertension diagnosed by echocardiography: a retrospective cohort study in a single center from China.
Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- How severity and classification of pulmonary hypertension affect pregnancy outcomes: a systematic review and timeline.International journal of obstetric anesthesia · 2024Pooled it
- Pregnancy feasibility in women with mild pulmonary arterial hypertension: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Hyperuricemia and Hypoxic Pulmonary Hypertension: Pathogenic Links, Clinical Evidence, and Emerging Therapeutic Insights.Cardiovascular drugs and therapy · 2026Review
- Risk stratification and multidisciplinary management strategies for pregnancy complicated by pulmonary arterial hypertension: a narrative review.Frontiers in endocrinology · 2026Review
- Pregnancy in patients with pulmonary hypertension: a systematic review and meta-analysis with meta-regression.Journal of thoracic disease · 2025Article
- Long-term maternal and fetal outcomes of pulmonary hypertension in pregnancy in the southwest plateau area of China: a retrospective study.BMC pulmonary medicine · 2025Article
- Maternal and Fetal Outcomes in Pregnant Women with Pulmonary Arterial Hypertension: A Single-Center Experience and Review of Current Literature.Anatolian journal of cardiology · 2022Review
- Pregnant outcomes of critically ill pregnant patients with pulmonary hypertension: A multicenter retrospective study.Frontiers in cardiovascular medicine · 2022Article
- Early Assessment of Cardiac Function by Echocardiography in Patients with Gestational Diabetes Mellitus.Computational and mathematical methods in medicine · 2022Article
- Targeting Myadm to Intervene Pulmonary Hypertension on Rats Before Pregnancy Alleviates the Effect on Their Offspring's Cardiac-Cerebral Systems.Frontiers in pharmacology · 2021Article
- Is the maternal risk of pregnancy acceptable in patients with moderate pulmonary hypertension?Pulmonary circulationArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies suggest that pregnancy may not be absolutely contraindicated in women with moderate pulmonary hypertension. We aimed to evaluate the long-term outcomes of pregnant women with pulmonary hypertension diagnosed by echocardiography in our clinical department. Pregnant women with pulmonary hypertension, diagnosed by a pulmonary systolic arterial pressure > 30 mmHg via echocardiography, who were admitted in our department for termination of pregnancy or delivery between 2004 and 2016 were included in this retrospective cohort study. Demographic characteristics, clinical histories, perinatal outcomes, and follow-up outcomes after discharge were reported. The primary outcome was survival of the pregnant women after discharge. A total of 88 pregnant women with pulmonary hypertension were included in this cohort study. The women were categorized into severe and moderate pulmonary hypertension groups according to their pulmonary systolic arterial pressure at admission. Women with severe pulmonary hypertension were significantly more likely to have deteriorated cardiac function and higher incidence of neonatal complications during the perinatal periods (p < 0.05). During a median follow-up of 26 months, the mortality rate was significantly higher in women with severe pulmonary hypertension (p < 0.05). However, the accumulated survival rate was >90% for women with moderate pulmonary hypertension within the follow-up period. Multivariate Cox regression analyses showed that poor cardiac function before pregnancy, irregular antenatal care, and hyperuricemia were independent mortality risk factors for women with pulmonary hypertension after discharge. In conclusion, the long-term survival of pregnant women with moderate pulmonary hypertension diagnosed by echocardiography was considered acceptable in this cohort. Our findings suggest that pregnancy might not be absolutely contraindicated in women with moderate pulmonary hypertension.
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