Evidence map›Paper›PMID 33616872›Full record

ArticleNeurotoxicity research2021

Astrocyte Intracellular Ca

Frederico R Ferreira, Alexander Cupido, Bogdan Catalin, Wilson A Silva, Frank Kirchhoff, Elaine A Del-Bel, Francisco S Guimarães

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Frederico R FerreiraOswaldo Cruz Institute, Oswaldo Cruz Foundation, 21040-900, Rio de Janeiro-RJ, Brazil. frederico.ferreira@ioc.fiocruz.br.ORCID http://orcid.org/0000-0001-5098-9775
Alexander CupidoMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
Bogdan CatalinMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
Wilson A SilvaDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Frank KirchhoffMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
Elaine A Del-BelDepartment of Morphology, Physiology, Basic and Pathology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.
Francisco S GuimarãesDepartment of Pharmacology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.
Saarland University · DEUniversidade de São Paulo · BRFundação Oswaldo Cruz · BRNational Council for Scientific and Technological Development · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although monoaminergic-based antidepressant drugs are largely used to treat major depressive disorder (MDD), their mechanisms are still incompletely understood. Intracellular Ca

Indexed as

AnimalsAntidepressive AgentsAstrocytesCalcium SignalingDepressionHEK293 CellsHippocampusHumansMaleMiceMice, Inbred C57BLOrgan Culture TechniquesRatsRats, WistarReceptor, trkBTreatment OutcomeAntidepressive AgentsNtrk2 protein, ratReceptor, trkBAstrocyteCalmodulin 1ImipramineIntracellular calciumMajor depressive disorder

Identifiers

PMID33616872
OpenAlexW3132252523

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.