ArticleCirculation. Genomic and precision medicine2021
Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K
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Article in Circulation. Genomic and precision medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Integrated Methylome and Transcriptome Analysis in Chronic Chagas Cardiomyopathy Uncovers Alterations in Heart Development.The Journal of infectious diseases · 2026Article
- Identification of a Novel Genetic Variant Responsible for Familial Atrial Fibrillation.The Canadian journal of cardiology · 2026Article
- Review
- Functional assays inGenome research · 2025Review
- Evaluation of the Potential Targets of Shenxian-Shengmai Oral Liquid in Treating Sick Sinus Syndrome Based on Network Pharmacology and Molecular Docking.Food science & nutrition · 2024Article
- Top stories on intracellular potassium channels in cardiac arrhythmia.Heart rhythm · 2024Article
- Exosomal Preconditioning of Human iPSC-Derived Cardiomyocytes Beneficially Alters Cardiac Electrophysiology and Micro RNA Expression.International journal of molecular sciences · 2024Article
- Cardiac conduction diseases: understanding the molecular mechanisms to uncover targets for future treatments.Expert opinion on therapeutic targets · 2024Review
- The BKPhysiological reports · 2024Article
- Exploring the Impact of BKInternational journal of molecular sciences · 2024Review
- Cardiac arrhythmogenesis: roles of ion channels and their functional modification.Frontiers in physiology · 2024Review
- Nernst-Planck-Gaussian finite element modelling of CaFrontiers in physiology · 2024Article
- Feedback contributions to excitation-contraction coupling in native functioning striated muscle.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Regulation of Papillary Muscle Contractility by NAD and Ammonia Interplay: Contribution of Ion Channels and Exchangers.Membranes · 2022Article
- Inter-Species Rescue of Mutant Phenotype-The Standard for Genetic Analysis of Human Genetic Disorders inInternational journal of molecular sciences · 2022Review
- Modeling Human Cardiac Arrhythmias: Insights from Zebrafish.Journal of cardiovascular development and disease · 2022Review
- Piezo buffers mechanical stress via modulation of intracellular CaFrontiers in physiology · 2022Article
- Drivers of Sinoatrial Node Automaticity in Zebrafish: Comparison With Mechanisms of Mammalian Pacemaker Function.Frontiers in physiology · 2022Article
- Atrial Fibrillation Genomics: Discovery and Translation.Current cardiology reports · 2021Review
Corrections and comments
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Authors and funding
26 authors at 8 institutions in 4 countries.
Santiago Pineda *Development, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Vesna Nikolova-Krstevski *Victor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Christiana Leimena *Victor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Andrew J AtkinsonInstitute of Cardiovascular Sciences, University of Manchester, United Kingdom (A.J.A., H.D.).
Ann-Kristin AltekoesterVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Charles D CoxVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Arie JacobyVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Inken G HuttnerVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Yue-Kun JuBosch Institute, University of Sydney, Camperdown (Y.-K.J., D.G.A.).
Magdalena SokaVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Monique OhanianVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Gunjan TrivediVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Sreehari KalvakuriDevelopment, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Katja BirkerDevelopment, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Renee JohnsonVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Peter MolenaarFaculty of Health, Queensland University of Technology (P.M.).
Dennis KucharCardiology Department, St Vincent's Hospital, Darlinghurst (D.K., D.F.).
David G AllenBosch Institute, University of Sydney, Camperdown (Y.-K.J., D.G.A.).
Dirk F van HeldenUniversity of Newcastle and Hunter Medical Research Institute, NSW, Australia (D.F.v.H.).
Richard P HarveyVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Adam P HillVictor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Rolf BodmerDevelopment, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Georg VoglerDevelopment, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Halina DobrzynskiInstitute of Cardiovascular Sciences, University of Manchester, United Kingdom (A.J.A., H.D.).
Karen Ocorr *Development, Aging & Regeneration Program, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA (S.P., S.K., K.B., R.B., G.V., K.O.).
Diane Fatkin *Victor Chang Cardiac Research Institute, Darlinghurst (V.N.-K., C.L., A.-K.A., C.D.C., A.J., I.G.H., M.S., M.O., G.T., R.J., R.P.H., A.P.H., D.F.).
Victor Chang Cardiac Research Institute · AUDiscovery Institute · USRobert Bosch (Australia) · AUAi2 (United Kingdom) · GBHunter Medical Research Institute · AUJagiellonian University · PLQueensland University of Technology · AUSt Vincent's Hospital Sydney · AU
Funding
HEART DEVELOPMENT IN DROSOPHILAR01HL054732 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BODMER, ROLF · 1995 to 2024
$11.3MCellular/molecular substrates linking channel dysfunction and pathological cardiac remodelingR01HL132241 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI OCORR, KAREN · 2017 to 2020
$1.9MGenetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart FailureR01HL149992 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BODMER, ROLF · 2020 to 2023
$1.9MCellular Mediators of Cardiac Aging and Arrhythmia in DrosophilaR21AG061598 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI OCORR, KAREN · 2019 to 2020
$536kNHLBI NIH HHS R01 HL054732NHLBI NIH HHS R01 HL132241NHLBI NIH HHS R01 HL149992NIA NIH HHS R21 AG061598
Abstract
background
methodsThe
resultsA complex
conclusionsOur data point to a highly conserved role of K
Indexed as
Action PotentialsAnimalsAtrial FibrillationAtrial FunctionEmbryo, NonmammalianHeart AtriaHumansIndolesLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMiceMyocardial ContractionPedigreePolymorphism, GeneticRNA InterferenceRNA, Small InterferingSinoatrial NodeIndolesLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitspaxillineRNA, Small InterferingZebrafish Proteinsaction potentialsbradycardiachromosomesligandsmorbidity
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.