Evidence map›Paper›PMID 33629947›Full record

Trial reportMicrobial genomics2021

Genomic relatedness and clinical significance of

Carine R Mores, Travis K Price, Birte Wolff, Thomas Halverson, Roberto Limeira, Linda Brubaker, Elizabeth R Mueller, Catherine Putonti, Alan J Wolfe

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Microbial genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Genomic identification and characterization of Streptococcus oralis group that causes intraamniotic infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  3. Re-evaluation of boundaries ofInternational journal of systematic and evolutionary microbiology · 2025
    Article
  4. Article
  5. Evidence ofMicrobial genomics · 2024
    Article
  6. Evidence ofMicrobial genomics · 2024
    Article
  7. Review
  8. Insights into the role ofFrontiers in cellular and infection microbiology · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Carine R MoresDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Travis K PriceDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Birte WolffPresent address: Swedish Hospital, NorthShore University, Suite 605, 5140 N California Avenue, Chicago, IL 60625, USA.
Thomas HalversonDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Roberto LimeiraLoyola Genomics Facility, Loyola University Chicago, Maywood, IL 60153, USA.
Linda BrubakerDepartment of Obstetrics, Gynecology and Reproductive Sciences, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California San Diego, La Jolla, CA, USA.
Elizabeth R MuellerDepartment of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, IL 60153, USA.
Catherine PutontiDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Alan J WolfeDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Loyola University Chicago · USLoyola University Medical Center · USSIB Swiss Institute of Bioinformatics · CHUniversity of California, Los Angeles · USUniversity of California San Diego · US

Funding

The Female Urinary Microbiome and Urinary IncontinenceR01DK104718 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, WOLFE, ALAN J · 2016 to 2020
$3.1M
NIDDK NIH HHS R01 DK104718
6 · The paper itself

Abstract

Research into the lower urinary tract (LUT) microbiota has primarily focused on its relationship to LUT symptoms (LUTS), taking snapshots of these communities in individuals with and without LUTS. While certain bacterial taxa have been associated with LUTS, or the lack thereof, the temporal dynamics of this community were largely unknown. Recently, we conducted a longitudinal study and found that vaginal intercourse resulted in a shift in species richness and diversity within the LUT microbiota. This is particularly relevant as frequent vaginal intercourse is a major risk factor for urinary tract infection (UTI) in premenopausal women (Aydin

Indexed as

AdultFemaleGenome, BacterialGenomicsHumansLongitudinal StudiesMaleMicrobiotaMouthSexual BehaviorSexual PartnersStreptococcus mitisUrinary Tract InfectionsVaginalower urinary tractmetaculturomicsmicrobiomesexStreptococcus mitisurinary microbiota

Identifiers

PMID33629947
PMCPMC8190612
OpenAlexW3130012397

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.