Evidence mapPaperPMID 33634475Full record

ReviewJournal of cellular physiology2021

Pathogenesis and prospects for therapeutic clinical application of noncoding RNAs in glaucoma: Systematic perspectives.

Rong Rong, Mengxiao Wang, Mengling You, Haibo Li, Xiaobo Xia, Dan Ji

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of cellular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Potential roles of lncRNA MALAT1-miRNA interactions in ocular diseases.Journal of cell communication and signaling · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rong RongEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0002-6705-6696
Mengxiao WangEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.
Mengling YouEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.
Haibo LiEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0002-6969-9775
Xiaobo XiaEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.
Dan JiEye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0001-5901-3672
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noncoding ribonucleic acids (ncRNAs) are an increasingly studied class of RNA molecules with extensive biological activities, including important roles in human development, health, and disease. Glaucoma is a neurodegenerative disease of the retina, and one of the leading causes of blindness worldwide. However, the specific roles of ncRNAs in the development and progression of glaucoma are unclear, and related reports are fragmented. An in-depth understanding of ncRNAs participating in the pathogenesis and progression of glaucoma would be helpful for opening up new avenues to facilitate the early diagnosis and clinical treatment. Therefore, in this review, we aimed to discuss the current research progress, the potentialfuture clinical applications and the research limitations of three critical classes of ncRNAs in glaucoma, namely microRNAs, long noncoding RNAs, and circular RNAs.

Indexed as

AnimalsBiomarkersEarly DiagnosisGene Expression RegulationGlaucomaHumansMicroRNAsPredictive Value of TestsPrognosisRetinaRNA, CircularRNA, Long NoncodingBiomarkersMicroRNAsRNA, CircularRNA, Long Noncodingcircular RNAsglaucomalong noncoding RNAsmicroRNAs

Identifiers

PMID33634475
PMCPMC8451868
OpenAlexW3131083785

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.