Evidence map›Paper›PMID 33637436›Full record

ArticleJournal of the American Pharmacists Association : JAPhA

Statin nonadherence in Latino and noncitizen neighborhoods in New York City, Los Angeles, and Chicago, 2012-2016.

Jenny S Guadamuz, Ramon A Durazo-Arvizu, Martha L Daviglus, Gregory S Calip, Edith A Nutescu, Dima M Qato

Abstract read
In one paragraph

Article in Journal of the American Pharmacists Association : JAPhA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jenny S Guadamuz
Ramon A Durazo-Arvizu
Martha L Daviglus
Gregory S Calip
Edith A Nutescu
Dima M Qato

Funding

Training in CVD Epidemiology & Related Chronic Diseases in Minority PopulationsT32HL125294 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DAVIGLUS, MARTHA L · 2015 to 2019
$1.3M
Pharmacy Accessibility and Disparities in Adherence to Cardiovascular Medications in ElderlyR21AG049283 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI QATO, DIMA MAZEN · 2015 to 2016
$443k
NHLBI NIH HHS T32 HL125294NIA NIH HHS R21 AG049283
6 · The paper itself

Abstract

backgroundLatino adults, especially immigrants without citizenship (i.e., noncitizens), experience considerable barriers to health care, including medications. Inequitable access to medications, especially statins, may exacerbate disparities in cardiovascular disease. Despite this, little is known about medication nonadherence in Latino neighborhoods, especially those with large noncitizen populations.

objectivesTo estimate nonadherence to statins in Latino neighborhoods and evaluate differences on the basis of their noncitizen population.

methodsWe conducted a retrospective cohort study among 48,161 adults who lived in predominately Latino neighborhoods in New York City, Los Angeles, and Chicago and who initiated statin therapy from January 2012 to December 2015 using IQVIA LifeLink. Statin nonadherence was defined as a proportion of days covered amounting to less than 80% over 12 months. We focused on differences between neighborhoods with high noncitizen concentrations (areas where noncitizens are at least 35% of the adult population) and other Latino neighborhoods. We examined associations using logistic regressions adjusted for individual (e.g., payment method) and neighborhood characteristics (e.g., poverty).

resultsIndividuals living in neighborhoods with high noncitizen concentrations were more nonadherent to statins than those in Latino neighborhoods with fewer noncitizens (75.0% vs. 70.0%, adjusted odds ratio [aOR] 1.18, [95% CI 1.06-1.33]). These disparities were worse in New York City (77.7% vs. 69.1%, aOR 1.37, [95% CI 1.23-1.53]) and Chicago (76.1% vs. 68.8%, aOR 1.38, [95% CI 1.14-1.67]) than in Los Angeles (73.8% vs. 71.3%, aOR 1.10, [95% CI 1.01-1.20]).

conclusionNeighborhoods with large noncitizen populations have much higher rates of statin nonadherence than Latino neighborhoods with fewer noncitizens. These disparities were least pronounced in Los Angeles, where the county provides health care to all uninsured residents, including noncitizens without documentation to reside in the United States. Efforts to improve medication access in Latino neighborhoods should be multifocal and start by implementing state and local health care options for low-income residents, regardless of citizenship status.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsAdultChicagoHispanic or LatinoHumansLos AngelesNew York CityResidence CharacteristicsRetrospective StudiesUnited StatesHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID33637436
PMCPMC8273086

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.