Evidence map›Paper›PMID 33643307›Full record

ArticleFrontiers in immunology2020

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution.

Stephania Libreros, Ashley E Shay, Robert Nshimiyimana, David Fichtner, Michael J Martin, Nicholas Wourms, Charles N Serhan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
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  10. Linking Lipid Metabolism and Immune Function: New Insights into Chronic Respiratory Diseases.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Omega-3 and Sports: Focus on Inflammation.Life (Basel, Switzerland) · 2024
    Review
  17. 15-epi-lipoxin AFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stephania LibrerosCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Ashley E ShayCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Robert NshimiyimanaCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
David FichtnerCayman Chemical, Research and Development Department, Ann Arbor, MI, United States.
Michael J MartinCayman Chemical, Research and Development Department, Ann Arbor, MI, United States.
Nicholas WourmsCayman Chemical, Research and Development Department, Ann Arbor, MI, United States.
Charles N SerhanCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Cayman Chemical (United States) · USBrigham and Women's Hospital · USHarvard University · US

Funding

Resolution Mechanisms in Acute Inflammation: Resolution PharmacologyP01GM095467 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SERHAN, CHARLES NICHOLAS · 2011 to 2020
$14.8M
Bone Marrow Functions of Novel Pro-Resolving MediatorsK99HL153673 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIBREROS, STEPHANIA · 2020 to 2021
$247k
Novel Role of Pro-Resolving Lipid Mediators in Signaling LeukocytesF32HL142175 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIBREROS, STEPHANIA · 2018 to 2020
$156k
NHLBI NIH HHS F32 HL142175NHLBI NIH HHS K99 HL153673NIGMS NIH HHS P01 GM095467
6 · The paper itself

Abstract

The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation

Indexed as

Anti-Inflammatory AgentsFatty Acids, UnsaturatedApoptosisHumansInflammationMacrophagesNeutrophilsAnti-Inflammatory AgentsFatty Acids, Unsaturatedeicosapentaenoic acidlipid mediatorM2 macrophagesomega-3 fatty acidsphagocytespro-resolvingpro-resolving mediator

Identifiers

PMID33643307
PMCPMC7902526
OpenAlexW3127670241

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.