ReviewExperimental & molecular medicine2021
Zebrafish as an animal model for biomedical research.
Review in Experimental & molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 245 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
245 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Zebrafish models for congenital disorders of glycosylation (CDG): a systematic review.Orphanet journal of rare diseases · 2025Pooled it
- Unveiling the therapeutic potential of medicinal plants in zebrafish caudal fin regeneration and wound healing: a systematic review.Fish physiology and biochemistry · 2025Pooled it
- The effect of laboratory diet and feeding on growth parameters in juvenile zebrafish.Lab animal · 2024Pooled it
- Review
- Comparative developmental toxicity and oxidative stress of synthetic and natural yellow food colorants in zebrafish (Toxicology reports · 2026Article
- Article
- Unveiling Distinct Developmental and Cellular Impacts of Cisplatin on Zebrafish (Methods and protocols · 2026Article
- Impacts of variation in experimental parameters on larval zebrafish behavior: Enhancing rigor and reproducibility in neurobehavioral research.Behavioural processes · 2026Article
- A zebrafish module for genetic problem-solving.Journal of microbiology & biology education · 2026Article
- Mapping Double-Bond Positional Isomers of Phosphatidylcholines in Zebrafish Using OzMALDI Mass Spectrometry Imaging.Journal of the American Society for Mass Spectrometry · 2026Article
- Potential and challenges of Positron Emission Tomography beyond conventional preclinical and clinical imaging.Zeitschrift fur medizinische Physik · 2026Review
- Whole-Mount Immunostaining of Tyrosine Hydroxylase for Dopaminergic Neuron Analysis in Zebrafish Larvae.Bio-protocol · 2026Article
- Brain Spatial Genomics Atlases.Genes · 2026Review
- Gut-Microbial Responses to Acute Polyester Microplastic Exposure in Zebrafish: Dysbiosis, Opportunistic Bacteria, and Functional Impact.International journal of molecular sciences · 2026Article
- Multimodal optical imaging for the assessment of the teratogenic effects of ethanol on zebrafish development.Journal of biomedical optics · 2026Article
- A Novel BIRC6 Variant Impairs Apoptotic Regulation in Familial Premature Ovarian Insufficiency: Functional Validation in a CRISPR/Cas9 Zebrafish Model.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Ultra-high density perovskite nanowire array memristor-based multi-layer perceptron.Nature communications · 2026Article
- Article
- Overlapping expression and co-operative function of the zebrafish pcdh15 paralogs.Communications biology · 2026Article
- Evaluating the nanotoxicity and antioxidant pathway modulation of MnOScientific reports · 2026Article
185 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zebrafish have several advantages compared to other vertebrate models used in modeling human diseases, particularly for large-scale genetic mutant and therapeutic compound screenings, and other biomedical research applications. With the impactful developments of CRISPR and next-generation sequencing technology, disease modeling in zebrafish is accelerating the understanding of the molecular mechanisms of human genetic diseases. These efforts are fundamental for the future of precision medicine because they provide new diagnostic and therapeutic solutions. This review focuses on zebrafish disease models for biomedical research, mainly in developmental disorders, mental disorders, and metabolic diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.