Evidence mapPaperPMID 33652956Full record

ArticleDiagnostics (Basel, Switzerland)2021

Epicardial Adiposity in Relation to Metabolic Abnormality, Circulating Adipocyte FABP, and Preserved Ejection Fraction Heart Failure.

Jiun-Lu Lin, Kuo-Tzu Sung, Yau-Huei Lai, Chih-Hsuan Yen, Chun-Ho Yun, Cheng-Huang Su, Jen-Yuan Kuo, Chia-Yuan Liu, Chen-Yen Chien, Ricardo C Cury and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jiun-Lu LinDivision of Endocrinology and Metabolism, Department of Internal Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Kuo-Tzu SungDivision of Cardiology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Yau-Huei LaiDivision of Cardiology, Department of Internal Medicine, MacKay Memorial Hospital, Hsinchu 30071, Taiwan.
Chih-Hsuan YenDivision of Cardiology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Chun-Ho YunMackay Junior College of Medicine, Nursing, and Management, Taipei 11260, Taiwan.
Cheng-Huang SuDepartment of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.
Jen-Yuan KuoDepartment of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.
Chia-Yuan LiuDepartment of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.
Chen-Yen ChienDepartment of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.ORCID 0000-0002-9329-505X
Ricardo C CuryCardiovascular MRI and CT Program, Baptist Cardiac Vascular Institute, Miami, FL 33176, USA.
Hiram G BezerraCardiovascular Department, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.
Chung-Lieh HungDivision of Cardiology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.ORCID 0000-0002-2858-3493
Mackay Memorial Hospital · TWNational Taiwan University · TWUniversity Hospitals Cleveland Medical Center · US

Funding

MacKay Memorial Hospital 10271, 10248, 10220, 10253, 10375, 10358, E-102003Ministry of Science and Technology (Taiwan) NSC-101-2314-B-195-020, NSC103-2314-B-010-005-MY3, 103-2314-B-195-001-MY3, 101-2314-B-195 -020 -MY1, MOST 103-2314-B-195-006-MY3, and NSC102-2314-B-002-046-MY3, 106-2314-B-195 -008 -MY2, 108-2314-B-195-018-MY2
6 · The paper itself

Abstract

Epicardial adipose tissue (EAT) as a source of pro-inflammatory cytokines tightly linked to metabolic abnormalities. Data regarding the associations of EAT with adipocyte fatty acid-binding protein (A-FABP), a cytokine implicated in the cardiometabolic syndrome, might play an important part in mediating the association between EAT and cardiac structure/function in preserved ejection fraction heart failure (HFpEF). We conducted a prospective cohort study comprising 252 prospectively enrolled study participants classified as healthy (

Indexed as

adipocyte fatty acid-binding protein (A-FABP)epicardial adipose tissue (EAT)heart failure (HF)metabolic syndromepreserved ejection fraction heart failure (HFpEF)pro-inflammatory cytokinesstrainstrain rate

Identifiers

PMID33652956
PMCPMC7996796
OpenAlexW3135812748

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.