Evidence map›Paper›PMID 33658350›Full record

ArticleJournal of virology2021

Guinea pig cytomegalovirus protective T cell antigen GP83 is a functional pp65 homolog for innate immune evasion and pentamer dependent virus tropism.

K Yeon Choi, Nadia El-Hamdi, Julia Hornig, Alistair McGregor

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

K Yeon ChoiDepartment of Microbial Pathogenesis & Immunology, Texas A&M University, Health Science Center, College of Medicine, Bryan, Texas, United States of America.
Nadia El-Hamdi
Julia Hornig
Alistair McGregorDepartment of Microbial Pathogenesis & Immunology, Texas A&M University, Health Science Center, College of Medicine, Bryan, Texas, United States of America. mcgalistair2013@tamu.edu.ORCID https://orcid.org/0000-0002-5994-516X
Texas A&M Health Science Center · US

Funding

Development of a universal DISC vaccine strategy against congenital cytomegalovirusR01AI155561 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MCGREGOR, ALISTAIR · 2021 to 2025
$3.3M
CMV pentameric complex based vaccine strategies for prevention of congenital CMVR01HD090065 · NICHD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MCGREGOR, ALISTAIR · 2017 to 2021
$1.5M
Placental trophoblast infection and TLR mediated response to congenital CMVR01AI100933 · NIAID · UNIVERSITY OF MINNESOTA · PI MCGREGOR, ALISTAIR · 2012 to 2015
$1.5M
Development of an effective DISC vaccine strategy against congenital CMVR01AI098984 · NIAID · UNIVERSITY OF MINNESOTA · PI MCGREGOR, ALISTAIR · 2012 to 2015
$1.4M
NIAID NIH HHS R01 AI098984NIAID NIH HHS R01 AI100933NIAID NIH HHS R01 AI155561NICHD NIH HHS R01 HD090065
6 · The paper itself

Abstract

The guinea pig is the only small animal model for congenital CMV but requires species-specific guinea pig cytomegalovirus (GPCMV). Tegument protein GP83 is the presumed homolog of HCMV pp65 but gene duplication in the

Identifiers

PMID33658350
PMCPMC8139670
OpenAlexW3133935348

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.