Evidence map›Paper›PMID 33659250›Full record

ArticleFrontiers in cell and developmental biology2021

A Novel Function of TLR2 and MyD88 in the Regulation of Leukocyte Cell Migration Behavior During Wounding in Zebrafish Larvae.

Wanbin Hu, Leonie van Steijn, Chen Li, Fons J Verbeek, Lu Cao, Roeland M H Merks, Herman P Spaink

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Gut microbes · 2026
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  3. Quantifying Information Exchange Between Cells in Inflammaging.Bioengineering (Basel, Switzerland) · 2026
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  6. Review
  7. Article
  8. Article
  9. Article
  10. The Spike protein of SARS-CoV-2 signals via Tlr2 in zebrafish.Developmental and comparative immunology · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. A Fun-Guide to Innate Immune Responses to Fungal Infections.Journal of fungi (Basel, Switzerland) · 2022
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wanbin HuInstitute of Biology, Leiden University, Leiden, Netherlands.
Leonie van SteijnMathematical Institute, Leiden University, Leiden, Netherlands.
Chen LiLeiden Institute of Advanced Computer Science, Leiden University, Leiden, Netherlands.
Fons J VerbeekInstitute of Biology, Leiden University, Leiden, Netherlands.
Lu CaoLeiden Institute of Advanced Computer Science, Leiden University, Leiden, Netherlands.
Roeland M H MerksInstitute of Biology, Leiden University, Leiden, Netherlands.
Herman P SpainkInstitute of Biology, Leiden University, Leiden, Netherlands.
Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptor (TLR) signaling via myeloid differentiation factor 88 protein (MyD88) has been indicated to be involved in the response to wounding. It remains unknown whether the putative role of MyD88 in wounding responses is due to a control of leukocyte cell migration. The aim of this study was to explore

Indexed as

leukocyte migrationmacrophagesMyD88neutrophilstail woundingTLR2zebrafish

Identifiers

PMID33659250
PMCPMC7917198
OpenAlexW3132609170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.