Evidence map›Paper›PMID 33659531›Full record

ArticleBio-protocol2020

Testing Bone Formation Induction by Calvarial Injection Assay

Narelle E McGregor, Ingrid J Poulton, Emma C Walker, Natalie A Sims

Abstract read
In one paragraph

Article in Bio-protocol, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Narelle E McGregorBone Cell Biology and Disease Unit, St. Vincent's Institute of Medical Research, Melbourne, Australia.
Ingrid J PoultonBone Cell Biology and Disease Unit, St. Vincent's Institute of Medical Research, Melbourne, Australia.
Emma C WalkerBone Cell Biology and Disease Unit, St. Vincent's Institute of Medical Research, Melbourne, Australia.
Natalie A SimsBone Cell Biology and Disease Unit, St. Vincent's Institute of Medical Research, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone formation occurs during embryogenesis, skeletal growth and during the process of skeletal renewal throughout life. In the process of bone formation, osteoblasts lay down a collagen-containing matrix, termed osteoid, which is gradually hardened by incorporation of mineral crystals. Although osteoblasts can be induced to differentiate and to deposit mineral in culture, this system does not always provide results that reflect the ability of agents to stimulate bone formation

Indexed as

Bone formationCytokinesGrowth factorsOsteoblastOsteocyte

Identifiers

PMID33659531
PMCPMC7842514

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.