Evidence map›Paper›PMID 33660001›Full record

Trial reportInternational urogynecology journal2022

Pelvic floor muscle training as an adjunct to a midurethral sling: a single-blind randomised controlled trial.

Linda McLean, Marylène Charette, Kevin Varette, Kaylee Brooks, Marie-Andrée Harvey, Magali Robert, Kevin Baker, Andrew Day, Vincent Della Zazzera, Eric Sauerbrei and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06333353 (Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06333353 narecruitingnot on this mapstarted 2024, after this paper: background citation

Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of OttawaRan2024 to 2027Enrolled152ConditionsEndometriosis, PainArmsReal RepetitiveTranscranial Magnetic Stimulation 5 sessions, Sham RepetitiveTranscranial Magnetic Stimulation 5 sessions, Real RepetitiveTranscranial Magnetic Stimulation 10 sessions, Sham RepetitiveTranscranial Magnetic Stimulation 10 sessions
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Linda McLeanSchool of Rehabilitation Sciences, University of Ottawa, 200 Lees Avenue, Room E260C, Ottawa, ON, K1N 6N5, Canada. Linda.McLean@uottawa.ca.ORCID 0000-0003-0343-5168
Marylène CharetteInterdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Canada.
Kevin VaretteSchool of Rehabilitation Therapy, Queen's University, Kingston, Canada.
Kaylee BrooksSchool of Rehabilitation Sciences, University of Ottawa, 200 Lees Avenue, Room E260C, Ottawa, ON, K1N 6N5, Canada.
Marie-Andrée HarveyDepartment of Obstetrics and Gynaecology, Kingston General Hospital, Kingston, Canada.
Magali RobertDepartment of Obstetrics and Gynaecology, Foothills General Hospital, Calgary, Canada.
Kevin BakerDepartment of Obstetrics and Gynaecology, The Ottawa Hospital, Ottawa, Canada.
Andrew DayDepartment of Population Health Sciences, Queen's University, Kingston, Canada.
Vincent Della ZazzeraDepartment of Obstetrics and Gynaecology, Hôpital Montfort, Ottawa, Canada.
Eric SauerbreiDepartment of Radiology, Kingston General Hospital, Kingston, Canada.
Robert BrisonDepartment of Emergency Medicine, Kingston General Hospital, Kingston, Canada.
Kingston General Hospital · CAUniversity of Ottawa · CAQueen's University · CACalgary General Hospital · CAMontfort Hospital · CAOttawa Hospital · CA

Funding

CIHR 111168
6 · The paper itself

Abstract

introduction and hypothesisThis single-blind, randomised controlled trial was aimed at determining whether peri-operative physiotherapist-supervised pelvic floor muscle (PFM) training was superior to standard care (handout) in terms of improvements in stress urinary incontinence (SUI) symptoms, cure rate, and/or post-operative filling or voiding symptoms among women undergoing surgical mid-urethral sling (MUS) insertion for SUI.

methodsWomen with SUI were recruited from surgical wait lists at four participating urogynecology clinics. Participants were assessed at baseline (V1) then randomised (1:1 allocation) to receive supervised PFM training or a handout. Immediately following the 12-week intervention period (V2) and at 12 weeks following surgery (V3) the groups were compared based on the Female Lower Urinary Tract Symptoms (FLUTS) questionnaire total score and urinary incontinence, filling, and voiding subscale scores as well as on a standardised 30-min pad test administered by a blinded assessor. Intention-to-treat analyses were performed.

resultsA total of 52 participants were randomised to physiotherapy and 51 to the control group between December 2012 and August 2016. The groups were not different on any outcomes at V1 and all were improved at V3 compared with V1 (p < 0.001). At V3 the physiotherapy group reported significantly fewer UI symptoms (FLUTS UI subscale score) than the control group; yet, there were no group differences in FLUTS overall score or the pad test (p > 0.05). Based on a FLUTS UI subscale score <4, the cure rate at V3 was higher in the intervention group (73%) than in the control group (47%); (2.36 < OR < 3.47, p = 0.012). There were no group differences in cure rate at V3 based on a pad test (p = 0.27). No group differences were found in the filling or voiding symptoms at V3 (p > 0.05). No adverse events were reported.

conclusionPhysiotherapist-supervised PFM training improves SUI cure rates associated with surgical MUS insertion when considering symptoms of SUI, but does not improve post-operative continence function as measured by a pad test, nor does it lead to fewer post-operative voiding or filling symptoms.

Indexed as

Suburethral SlingsUrinary IncontinenceUrinary Incontinence, StressExercise TherapyFemaleHumansMalePelvic FloorSingle-Blind MethodTreatment OutcomeMid-urethral slingPelvic floor muscle exercisePhysical therapyPhysiotherapyStress urinary incontinence

Identifiers

PMID33660001
OpenAlexW3133530106

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.