Evidence map›Paper›PMID 33660120›Full record

ArticleSurgical endoscopy2022

Transoral endoscopic parathyroidectomy vestibular approach (TOEPVA) for primary hyperparathyroidism: Turkey's experience.

Özer Makay, Mehmet Zafer Sabuncuoğlu, Mehmet İlker Turan, Ismail Cem Sormaz, Murat Özdemir, Nurcihan Aygün, Serhat Buldur, Yiğit Türk, Demet Sarıdemir, Atakan Sezer and 7 more

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Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Özer MakayDivision of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Bornova, Izmir, Turkey. ozer.makay@ege.edu.tr.ORCID 0000-0002-6660-6748
Mehmet Zafer SabuncuoğluDivision of Endoscopic-Laparoscopic & Minimally Invasive Surgery, Department General Surgery, Suleyman Demirel University Hospital, Isparta, Turkey.
Mehmet İlker TuranElmali State Hospital, Antalya, Turkey.
Ismail Cem SormazDepartment of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Murat ÖzdemirDivision of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Bornova, Izmir, Turkey.
Nurcihan AygünDepartment of General Surgery, Health Sciences University Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, Istanbul, Turkey.
Serhat BuldurDepartment of General Surgery, Can Hospital, Izmir, Turkey.
Yiğit TürkDivision of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Bornova, Izmir, Turkey.
Demet SarıdemirDepartment of General Surgery, Akdeniz University Hospital, Antalya, Turkey.
Atakan SezerDepartment of General Surgery, School of Medicine, Trakya University, Edirne, Turkey.
Serkan TeksözDepartment of General Surgery, Cerrahpaşa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Mehmet UludağDepartment of General Surgery, Health Sciences University Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, Istanbul, Turkey.
İsmail ZihniDivision of Endoscopic-Laparoscopic & Minimally Invasive Surgery, Department General Surgery, Suleyman Demirel University Hospital, Isparta, Turkey.
Fatih TuncaDepartment of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Mehmet HacıyanlıDepartment of General Surgery, Izmir Katip Çelebi University Hospital, Izmir, Turkey.
Cumhur ArıcıDepartment of General Surgery, Akdeniz University Hospital, Antalya, Turkey.
Yasemin Giles ŞenyürekDepartment of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Istanbul University · TREge University · TRAkdeniz University Hospital · TRSağlık Bilimleri Üniversitesi · TRSüleyman Demirel University · TRIzmir Kâtip Çelebi University · TRIzmir University · TRTrakya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimParathyroid surgery has witnessed a significant evolution with the introduction of more efficacious preoperative localization imaging techniques and the use of rapid intraoperative parathormone assays. Parathyroid surgery can now be performed with the minimum of invasion. Through the adaptation of the transoral endoscopic thyroidectomy vestibular approach (TOETVA), the technique has now been adopted for parathyroid surgery, known as the transoral endoscopic parathyroidectomy vestibular approach (TOEPVA). We present here the initial experiences of 11 centers carrying out TOEPVA surgery in Turkey. MATERIALS AND

methodsParticipating in the study were 11 centers, all of which were tertiary care institutions carrying out endocrine surgery. A retrospective review was made of 35 primary hyperparathyroidism patients who underwent the TOEPVA procedure between July 2017 and January 2020.

resultsOf the total 35 patients, 32 patients underwent the TOEPVA procedure successfully. All patients but one were female, and the mean age was 47.2 (20-73) years. According to localization studies, 18 of the lesions were lower left, 12 were lower right, 3 were upper right and 2 were upper left. The mean operative time was 116 (30-225) min, and three cases were converted to an open procedure. Simultaneous thyroidectomy was performed in seven cases. The average PTH level dropped to normal within 20 min. after the resection in all cases. The complication rate was 19% (ecchymosis, subcutaneous emphysema, nasal bleeding, surgical site infection and seroma). There were neither recurrent nerve palsies, nor mental nerve root or branch injuries. The average hospital stay was 1 day. No persistence was documented on follow up.

conclusionTOEPVA is a "hidden scar" parathyroidectomy procedure that can be safely performed on parathyroid adenomas, in cases that have scar-related concerns. Having its own procedure-related complications, the procedure provides satisfactory objective results, particularly in centers experienced in endoscopic and endocrine surgery.

Indexed as

Hyperparathyroidism, PrimaryParathyroid NeoplasmsEndoscopyFemaleHumansMiddle AgedParathyroidectomyThyroidectomyTurkeyParathyroidectomyTOEPVATransoral endoscopic approach

Identifiers

PMID33660120
OpenAlexW3134400249

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.